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Human Ephrin A4 Protein, His Tag

Human Ephrin A4 Protein, His Tag

产品编号

KMP2975

别名

肝配蛋白A4, Human Ephrin A4 Protein, His Tag, Ephrin A4

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias肝配蛋白A4, Human Ephrin A4 Protein, His Tag, Ephrin A4
Catalog NumberKMP2975
Product DescriptionThe Human Ephrin A4 Protein(KMP2975) is produced in HEK293 Cells. The target gene encoding the human EFNA4 (NP_005218.1) (Met1-Gly171) is expressed with a polyhistidine tag at the C-terminus.
Molecular NameEphrin A4
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundEPH-related receptor tyrosine kinase ligand 4 (Ephrin-A4) also known as EFNA4, is a member of the Ephrin family. The Eph family receptor interacting proteins (ephrins) are a family of proteins that serve as the ligands of the Eph receptor, which compose the largest known subfamily of receptor protein-tyrosine kinases (RTKs). Eph/ephrin interactions are implicated in axon guidance, neural crest cell migration, establishment of segmental boundaries, and formation of angiogenic capillary plexi. Ephrin subclasses are further distinguished by their mode of attachment to the plasma membrane: ephrin-A ligands bind EphA receptors and are anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) linkage, whereas ephrin-B ligands bind EphB receptors and are anchored via a transmembrane domain. An exception is the EphA4 receptor, which binds both subclasses of ephrins. Ephrin-A4/EFNA4 functions as a cell surface GPI-bound ligand for Eph receptor, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight17.8 kDa

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