Human PRNP Protein, hFc Tag
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产品编号
KMP2973
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别名
朊蛋白, Human PRNP Protein, hFc Tag, PRNP
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规格
- 50ug
- 100ug
- 200ug
Alias | 朊蛋白, Human PRNP Protein, hFc Tag, PRNP |
Catalog Number | KMP2973 |
Product Description | The Human PRNP Protein(KMP2973) is produced in HEK293 Cells. The target gene encoding the human PRNP (NP_000302.1) (Met1-Gly229) is expressed with the Fc region of human IgG1 at the C-terminus. |
Molecular Name | PRNP |
Species | Human |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >90% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | Prion protein (PRNP) gene is well known for affecting mammal transmissible spongiform encephalopathies (TSE), and is also reported to regulate phenotypic traits (e.g. growth traits) in healthy ruminants. PRNP is fundamental in the pathogenesis of transmissible spongiform encephalopathies. Generally, PRNP gene is associated with prion diseases, whereas variants of the PRNP gene may also explain some cases of Alzheimer disease (AD) and frontotemporal dementia (FTD) in Caucasian populations. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 49.7 kDa |