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Human GGH Protein, His Tag

Human GGH Protein, His Tag

产品编号

KMP2972

别名

γ-谷氨酰水解酶, Human GGH Protein, His Tag, GGH

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Aliasγ-谷氨酰水解酶, Human GGH Protein, His Tag, GGH
Catalog NumberKMP2972
Product DescriptionThe Human GGH Protein(KMP2972) is produced in HEK293 Cells. The target gene encoding the human GGH (NP_003869.1) (Met1-Asp318) is expressed with a polyhistidine tag at the C-terminus.
Molecular NameGGH
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
Formulation20mM Tris, 150mM NaCl, pH8.0
Backgroundgamma-Glutamyl hydrolase (GGH) regulates intracellular folates and antifolates such as methotrexate (MTX) for proper nucleotide biosynthesis and antifolate-induced cytotoxicity, respectively. GGH is a ubiquitously-expressed enzyme that regulates intracellular folate metabolism for cell proliferation, DNA synthesis, and repair. cytoplasmic GGH might play a relevant role in the development and progression of invasive breast cancer.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight35.1 kDa

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