Human GGH Protein, His Tag
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产品编号
KMP2972
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别名
γ-谷氨酰水解酶, Human GGH Protein, His Tag, GGH
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规格
- 50ug
- 100ug
- 200ug
Alias | γ-谷氨酰水解酶, Human GGH Protein, His Tag, GGH |
Catalog Number | KMP2972 |
Product Description | The Human GGH Protein(KMP2972) is produced in HEK293 Cells. The target gene encoding the human GGH (NP_003869.1) (Met1-Asp318) is expressed with a polyhistidine tag at the C-terminus. |
Molecular Name | GGH |
Species | Human |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >95% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | 20mM Tris, 150mM NaCl, pH8.0 |
Background | gamma-Glutamyl hydrolase (GGH) regulates intracellular folates and antifolates such as methotrexate (MTX) for proper nucleotide biosynthesis and antifolate-induced cytotoxicity, respectively. GGH is a ubiquitously-expressed enzyme that regulates intracellular folate metabolism for cell proliferation, DNA synthesis, and repair. cytoplasmic GGH might play a relevant role in the development and progression of invasive breast cancer. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 35.1 kDa |