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Human GBA Protein, His Tag

Human GBA Protein, His Tag

产品编号

KMP2966

别名

葡萄糖神经酰胺酶β1, Human GBA Protein, His Tag, GBA

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias葡萄糖神经酰胺酶β1, Human GBA Protein, His Tag, GBA
Catalog NumberKMP2966
Product DescriptionThe Human GBA Protein(KMP2966) is produced in HEK293 Cells. The target gene encoding the human GBA (NP_000148.2) (Ala40-Gln536) is expressed with a polyhistidine tag at the C-terminus.
Molecular NameGBA
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundMutations in the GBA gene, encoding the lysosomal hydrolase glucocerebrosidase (GCase), are the most common known genetic risk factor for Parkinson's disease (PD) and dementia with Lewy bodies (DLB). ASAH1 (acid ceramidase 1) and GBA2 (glucocerebrosidase 2) enzymes that mediate glucosylsphingosine production and metabolism are attractive therapeutic targets for treating mutant GBA-associated PD.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight57 kDa

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