Human GBA Protein, His Tag
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产品编号
KMP2966
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别名
葡萄糖神经酰胺酶β1, Human GBA Protein, His Tag, GBA
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规格
- 50ug
- 100ug
- 200ug
Alias | 葡萄糖神经酰胺酶β1, Human GBA Protein, His Tag, GBA |
Catalog Number | KMP2966 |
Product Description | The Human GBA Protein(KMP2966) is produced in HEK293 Cells. The target gene encoding the human GBA (NP_000148.2) (Ala40-Gln536) is expressed with a polyhistidine tag at the C-terminus. |
Molecular Name | GBA |
Species | Human |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >95% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | Mutations in the GBA gene, encoding the lysosomal hydrolase glucocerebrosidase (GCase), are the most common known genetic risk factor for Parkinson's disease (PD) and dementia with Lewy bodies (DLB). ASAH1 (acid ceramidase 1) and GBA2 (glucocerebrosidase 2) enzymes that mediate glucosylsphingosine production and metabolism are attractive therapeutic targets for treating mutant GBA-associated PD. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 57 kDa |