Human BTLA Protein, hFc Tag_天津卡梅德科技发展有限公司

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Human BTLA Protein, hFc Tag

Human BTLA Protein, hFc Tag

产品编号

KMP2947

别名

B和T淋巴细胞衰减因子, Human BTLA Protein, hFc Tag, BTLA

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	B和T淋巴细胞衰减因子, Human BTLA Protein, hFc Tag, BTLA
Catalog Number	KMP2947
Product Description	The Human BTLA Protein(KMP2947) is produced in HEK293 Cells. The target gene encoding the human BTLA (NP_001078826.1) (Met1-Thr134) is expressed with the Fc region of human IgG1 at the C-terminus.
Molecular Name	BTLA
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>90% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	BTLA is a inhibitory molecule which belongs to the Ig superfamily. It down-modulates immune responses. As such, reagents that regulate the binding of BTLA to its ligand or alter BTLA signaling have significant therapeutic promise. BTLA is crucial to understand the mechanism(s) of action of these antibodies before attempting clinical applications. BTLA is not expressed by naive T cells, but it is induced during activation and remains expressed on T helper type 1 (T(H)1) but not T(H)2 cells. BTLA is a third inhibitory receptor on T lymphocytes with similarities to cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and programmed death 1 (PD-1).
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	38.8 kDa

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