Human Thrombomodulin Protein, His Tag_天津卡梅德科技发展有限公司

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Human Thrombomodulin Protein, His Tag

Human Thrombomodulin Protein, His Tag

产品编号

KMP2943

别名

血栓调节蛋白, Human Thrombomodulin Protein, His Tag, Thrombomodulin

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	血栓调节蛋白, Human Thrombomodulin Protein, His Tag, Thrombomodulin
Catalog Number	KMP2943
Product Description	The Human Thrombomodulin Protein(KMP2943) is produced in HEK293 Cells. The target gene encoding the human THBD (NP_000352.1) (Met1-Ser515) is expressed with a polyhistidine tag at the C-terminus.
Molecular Name	Thrombomodulin
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>90% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Thrombomodulin, also known as THBD (CD141), is an integral membrane protein that reduces blood coagulation by converting thrombin to an anticoagulant enzyme from a procoagulant enzyme. Thrombomodulin is expressed on the surface of endothelial cells and serves as a cofactor for thrombin. It is also expressed on human mesothelial cell, monocyte and a dendritic cell subset. Thrombomodulin functions as a cofactor in the thrombin-induced activation of protein C in the anticoagulant pathway by forming a 1:1 stoichiometric complex with thrombin. Thrombomodulin also regulates C3b inactivation by factor I. Mutations in the thrombomodulin gene have also been reported to be associated with atypical hemolytic-uremic syndrome.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	53.54 kDa

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