Human FAM3D Protein, His Tag
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产品编号
KMP2912
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别名
FAM3代谢调节信号分子D, Human FAM3D Protein, His Tag, FAM3D
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规格
- 50ug
- 100ug
- 200ug
Alias | FAM3代谢调节信号分子D, Human FAM3D Protein, His Tag, FAM3D |
Catalog Number | KMP2912 |
Product Description | The Human FAM3D Protein(KMP2912) is produced in HEK293 Cells. The target gene encoding the human FAM3D (Q96BQ1-1) (Met 1-Phe 224) is fused with a polyhistidine tag at the C-terminus |
Molecular Name | FAM3D |
Species | Human |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >95% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | Family with sequence similarity 3 (FAM3) family is a novel cytokine-like gene family, which has four genes in this family, FAM3A, FAM3B, FAM3C, and FAM3D, each encoding a protein (224-235 amino acids) with a hydrophobic leader sequence. It had indicated that FAM3B/PANDER (pancreatic derived factor) is highly expressed in pancreas, and FAM3A and FAM3C in almost all tissues. FAM3D is abundantly expressed in placenta and weakly expressed in small intestine. Immunohistochemistry showed that FAM3A is expressed prominently in the vascular endothelium, particularly capillaries. FAM3A and FAM3B protein were both localized to the islets of Langerhans of the endocrine pancreas. Recombinant FAM3B protein has delayed effects on beta-cell function. FAM3C is involved in retinal laminar formation processes in vertebrates. NFATC2, SCP2, CACNA1C, TCRA, POLE, and FAM3D, were associated with narcolepsy. Some of these associations were further supported by gene expression analyses and an association study in essential hypersomnia (EHS), CNS hypersonia similar to narcolepsy. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 23.4 kDa |