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Human FAM3D Protein, His Tag

Human FAM3D Protein, His Tag

产品编号

KMP2912

别名

FAM3代谢调节信号分子D, Human FAM3D Protein, His Tag, FAM3D

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
AliasFAM3代谢调节信号分子D, Human FAM3D Protein, His Tag, FAM3D
Catalog NumberKMP2912
Product DescriptionThe Human FAM3D Protein(KMP2912) is produced in HEK293 Cells. The target gene encoding the human FAM3D (Q96BQ1-1) (Met 1-Phe 224) is fused with a polyhistidine tag at the C-terminus
Molecular NameFAM3D
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundFamily with sequence similarity 3 (FAM3) family is a novel cytokine-like gene family, which has four genes in this family, FAM3A, FAM3B, FAM3C, and FAM3D, each encoding a protein (224-235 amino acids) with a hydrophobic leader sequence. It had indicated that FAM3B/PANDER (pancreatic derived factor) is highly expressed in pancreas, and FAM3A and FAM3C in almost all tissues. FAM3D is abundantly expressed in placenta and weakly expressed in small intestine. Immunohistochemistry showed that FAM3A is expressed prominently in the vascular endothelium, particularly capillaries. FAM3A and FAM3B protein were both localized to the islets of Langerhans of the endocrine pancreas. Recombinant FAM3B protein has delayed effects on beta-cell function. FAM3C is involved in retinal laminar formation processes in vertebrates. NFATC2, SCP2, CACNA1C, TCRA, POLE, and FAM3D, were associated with narcolepsy. Some of these associations were further supported by gene expression analyses and an association study in essential hypersomnia (EHS), CNS hypersonia similar to narcolepsy.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight23.4 kDa

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