Human Neuregulin-1 Protein_天津卡梅德科技发展有限公司

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Human Neuregulin-1 Protein

Human Neuregulin-1 Protein

产品编号

KMP2901

别名

神经调节素1, Human Neuregulin-1 Protein, Neuregulin-1

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	神经调节素1, Human Neuregulin-1 Protein, Neuregulin-1
Catalog Number	KMP2901
Product Description	The Human Neuregulin-1 Protein(KMP2901) is produced in HEK293 Cells. The target gene encoding the N-terminal fragment (Ser2-Lys246) of human NRG1 isoform beta1 (Q02297-6) is expressed. The purified protein is biotinylated in vitro.
Molecular Name	Neuregulin-1
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>75% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a 44-kD glycoprotein that interacts with the NEU / ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. NRG1 is a trophic factor that has been implicated in neural development, neurotransmission, and synaptic plasticity. NRG1 has multiple isoforms that are generated by the usage of different promoters and alternative splicing of a single gene. Neuregulin 1 (NRG1) is essential for the development and function of multiple organ systems, and its dysregulation has been linked to diseases such as cancer and schizophrenia. NRG1 is a schizophrenia candidate gene and plays an important role in brain development and neural function. Schizophrenia is a complex disorder, with etiology likely due to epistasis.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	26.8 kDa

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