Human CSH1 Protein, His Tag_天津卡梅德科技发展有限公司

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Human CSH1 Protein, His Tag

Human CSH1 Protein, His Tag

产品编号

KMP2900

别名

绒毛膜促生长激素 1, Human CSH1 Protein, His Tag, CSH1

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	绒毛膜促生长激素 1, Human CSH1 Protein, His Tag, CSH1
Catalog Number	KMP2900
Product Description	The Human CSH1 Protein(KMP2900) is produced in HEK293 Cells. The target gene encoding the human CSH1 (NP_001308.1) (Met1-Phe217) is expressed, fused with a polyhistidine tag at the C-terminus. The purified protein is biotinylated in vitro.
Molecular Name	CSH1
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>85% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Chorionic somatomammotropin hormone, also known as Choriomammotropin, Lactogen, Placental lactogen and CSH1, is a secreted protein which belongs to thesomatotropin / prolactin family. CSH1 is produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization. The CSH1 gene is member of the GH gene cluster on 17q, which consists of two growth hormone genes and three CSH genes. Genomic alterations in the GH cluster are well known, causing different phenotypes depending on the size of the deletion and the genes involved. The increased prevalence of hemizygosity of CSH1 in population in comparison to controls indicates a role for CSH1 haploinsufficiency in the etiology of growth retardation. Investigation of CSH1 deletions in further SRS and growth retarded patients will enable us to establish under which circumstances haploinsufficiency of CSH1 is likely to result in clinical changes.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	23.7 kDa

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