Human NCR2 Protein, His Tag_天津卡梅德科技发展有限公司

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Human NCR2 Protein, His Tag

Human NCR2 Protein, His Tag

产品编号

KMP2896

别名

天然细胞毒性触发受体 2, Human NCR2 Protein, His Tag, NCR2

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	天然细胞毒性触发受体 2, Human NCR2 Protein, His Tag, NCR2
Catalog Number	KMP2896
Product Description	The Human NCR2 Protein(KMP2896) is produced in HEK293 Cells. The target gene encoding the human NCR2 (NP_004819.2) extracellular domain (Met1-Pro190) is fused with a polyhistidine tag at the C-terminus. The purified protein is biotinylated in vitro.
Molecular Name	NCR2
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>85% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Natural cytotoxicity triggering receptor 2 (NCR2), also known as Natural killer cell p44-related protein (NKp44), or CD336, is a member of the natural cytotoxicity receptor (NCR) family, which composed of one Ig-like extracellular domain, a transmembrane segment, and a cytoplasmic domain. It is a novel transmembrane glycoprotein belonging to the Immunoglobulin superfamily characterized by a single extracellular V-type domain. The cytoplasmic domain of NKp44 also contains a sequence that matches the immunoreceptor tyrosine-based inhibitory motif (ITIM) consensus. This Cytotoxicity-activating receptor may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. NKp44 is selectively expressed by IL-2-activated NK cells and may contribute to the increased efficiency of activated NK cells to mediate tumor cell lysis. Tumor cell recognition of the mutated NKp44 proteins was significantly reduced and correlated with their lower recognition of heparin.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	20 kDa

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