Human Factor IX Protein, hFc Tag
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产品编号
KMP2890
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别名
凝血因子 IX, Human Factor IX Protein, hFc Tag, Factor IX
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规格
- 50ug
- 100ug
- 200ug
Alias | 凝血因子 IX, Human Factor IX Protein, hFc Tag, Factor IX |
Catalog Number | KMP2890 |
Product Description | The Human Factor IX Protein(KMP2890) is produced in HEK293 Cells. The target gene encoding the human F9 (NP_000124.1) (Met1-Thr467) is expressed with the Fc region of human IgG1 at the C-terminus. |
Molecular Name | Factor IX |
Species | Human |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >95% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | Coagulation factor IX, also known as Christmas factor, Plasma thromboplastin component and PTC, is a secreted protein which belongs to the peptidase S1 family. Coagulation factor IX / F9 contains two EGF-like domains, one Gla (gamma-carboxy-glutamate) domain and one?peptidase S1 domain. Coagulation factor IX / F9 is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca2+ons, phospholipids, and factor VIIIa. Defects in Coagulation factor IX / F9 are the cause of thrombophilia due to factor IX defect which is a hemostatic disorder characterized by a tendency to thrombosis. Defects in Coagulation factor IX / F9 are also the cause of recessive X-linked hemophilia B ( HEMB ) which also known as Christmas disease. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 75.5 kDa |