Human CD138 Protein, His Tag, Avi Tag_天津卡梅德科技发展有限公司

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Human CD138 Protein, His Tag, Avi Tag

Human CD138 Protein, His Tag, Avi Tag

产品编号

KMP2886

别名

多聚体蛋白多糖 1, Human CD138 Protein, His Tag, Avi Tag, CD138

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	多聚体蛋白多糖 1, Human CD138 Protein, His Tag, Avi Tag, CD138
Catalog Number	KMP2886
Product Description	The Human CD138 Protein(KMP2886) is produced in HEK293 Cells. The target gene encoding the Human SDC1 (NP_002988.3) (Met1-Glu251) is expressed with a C-terminal polyhistidine tag followed by an Avi tag. The expressed protein is biotinylated in vivo by the Biotin-Protein ligase (BirA enzyme) which is co-expressed.
Molecular Name	CD138
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Syndecan-1 also known as SDC1 and CD138, is the most extensively studied member of the syndecan family. It is found mainly in epithelial cells, but its expression is developmentally regulated during embryonic development. Syndecan-1/SDC1/CD138 has been shown to mediate cell adhesion to several ECM molecules, and to act as a coreceptor for fibroblast growth factors, potent angiogenic growth factors involved also in differentiation. Syndecan-1/SDC1/CD138 expression is reduced during malignant transformation of various epithelia, and this loss correlates with the histological differentiation grade of squamous cell carcinomas, lacking from poorly differentiated tumours. In squamous cell carcinomas of the head and neck, positive syndecan-1 expression correlates with a more favourable prognosis. Experimental studies on the role of Syndecan-1 in malignant transformation have shown that Syndecan-1/SDC1/CD138 expression is associated with the maintenance of epithelial morphology, anchorage-dependent growth and inhibition of invasiveness in vitro.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	27.38 kDa

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