Human Clusterin Protein, His Tag_天津卡梅德科技发展有限公司

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Human Clusterin Protein, His Tag

Human Clusterin Protein, His Tag

产品编号

KMP2882

别名

丛生蛋白, Human Clusterin Protein, His Tag, Clusterin

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	丛生蛋白, Human Clusterin Protein, His Tag, Clusterin
Catalog Number	KMP2882
Product Description	The Human Clusterin Protein(KMP2882) is produced in HEK293 Cells. The target gene encoding the Human CLU (NP_001822.3) (Met1-Glu449) is expressed with a polyhistidine tag at the C-terminus.
Molecular Name	Clusterin
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Clusterin, also known as complement-associated protein SP-40, Complement cytolysis inhibitor, Apolipoprotein J, Testosterone-repressed prostate message 2, Aging-associated gene 4 protein, CLU and APOJ, is a secreted protein which belongs to the clusterin family. Clusterin/Apolipoprotein J/Apo-J is an enigmatic glycoprotein with a nearly ubiquitous tissue distribution and an apparent involvement in biological processes ranging from mammary gland involution to neurodegeneration in Alzheimer's disease. Its major form, a heterodimer, is secreted and present in physiological fluids, but truncated forms targeted to the nucleus have also been identified. Clusterin/Apolipoprotein J/Apo-J is a widely distributed glycoprotein with a wide range of biologic properties. A prominent and defining feature of clusterin is its marked induction in such disease states as glomerulonephritis, cystic renal disease, renal tubular injury, neurodegenerative conditions, atherosclerosis, and myocardial infarction. Upregulation of clusterin mRNA and protein levels detected in diverse disease states and in in vitro systems have led to suggestions that it functions in membrane lipid recycling, in apoptotic cell death, and as a stress-induced secreted chaperone protein, amongst others.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	51.51 kDa

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