Anti-Human GPNMB Extracellular Domain Recombinant Antibody
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产品编号
YR1224
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别名
科研级 Glembatumumab ( 格巴妥木单抗 ), Anti-GPNMB Extracellular Domain Recombinant Antibody, Research Grade Glembatumumab
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规格
- 1mg
- 5mg
产品介绍
| Catalog Number | YR1224 |
| Alias | 科研级 Glembatumumab ( 格巴妥木单抗 ), Anti-GPNMB Extracellular Domain Recombinant Antibody, Research Grade Glembatumumab |
| Size | 1mg, 5mg |
| Molecular Name | Glembatumumab |
| CAS Number | 1020264-78-1 |
| Target | GPNMB extracellular domain[Homo sapiens] |
| Antibody Isotype | IgG2 Kappa |
| Clonity | Monoclonal |
| Concentration | 1mg/ml |
| Purity | >95% as determined by SDS-PAGE |
| Storage Condition | It is recommended to aliquote and store at -20°C for long term storage. Avoid repeated freezing and thawing cycles. |
| Formulation | PBS, pH7.5 |
| Shipping Condition | Shipped on ice packs. |
| Background | Glembatumumab vedotin (also known as CDX-011 and CR011-vcMMAE) is an antibody-drug conjugate (ADC) that targets cancer cells expressing transmembrane glycoprotein NMB (GPNMB). In May 2010, the U.S FDA granted Fast Track designation to CDX-011 for the treatment of advanced, refractory, or resistant GPNMB-expressing breast cancer. |
| Remarks | This product is for research use only. |
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