Anti-Human LOXL2 Recombinant Antibody
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产品编号
YR1290
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别名
科研级 Simtuzumab ( 辛妥珠单抗 ), Anti-LOXL2 Recombinant Antibody, Research Grade Simtuzumab
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规格
- 1mg
- 5mg
| Catalog Number | YR1290 |
| Alias | 科研级 Simtuzumab ( 辛妥珠单抗 ), Anti-LOXL2 Recombinant Antibody, Research Grade Simtuzumab |
| Size | 1mg, 5mg |
| Molecular Name | Simtuzumab |
| CAS Number | 1318075-13-6 |
| Target | LOXL2[Homo sapiens] |
| Antibody Isotype | IgG4 Kappa |
| Clonity | Monoclonal |
| Concentration | 1mg/ml |
| Purity | >95% as determined by SDS-PAGE |
| Storage Condition | It is recommended to aliquote and store at -20°C for long term storage. Avoid repeated freezing and thawing cycles. |
| Formulation | PBS, pH7.5 |
| Shipping Condition | Shipped on ice packs. |
| Background | Simtuzumab (INN, formerly GS 6624) is a humanized monoclonal antibody designed for the treatment of fibrosis. It binds to LOXL2 and acts as an immunomodulator. In January 2016, Gilead Sciences terminated its Phase 2 clinical study in patients with idiopathic pulmonary fibrosis (IPF) due to lack of efficacy. |
| Application | FCM, IP, ELISA, Neut, FuncS |
| Remarks | This product is for research use only. |
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