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Anti-Human LOXL2 Recombinant Antibody

Anti-Human LOXL2 Recombinant Antibody

产品编号

YR1290

别名

科研级 Simtuzumab ( 辛妥珠单抗 ), Anti-LOXL2 Recombinant Antibody, Research Grade Simtuzumab

规格
  • 1mg
  • 5mg
产品介绍
Alias科研级 Simtuzumab ( 辛妥珠单抗 ), Anti-LOXL2 Recombinant Antibody, Research Grade Simtuzumab
Catalog NumberYR1290
Molecular NameSimtuzumab
CAS Number1318075-13-6
TargetLOXL2[Homo sapiens]
Antibody IsotypeIgG4 Kappa
ClonityMonoclonal
Size1mg, 5mg
Concentration1mg/ml
Purity>95% as determined by SDS-PAGE
Storage ConditionIt is recommended to aliquote and store at -20°C for long term storage. Avoid repeated freezing and thawing cycles.
FormulationPBS, pH7.5
Shipping ConditionShipped on ice packs.
BackgroundSimtuzumab (INN, formerly GS 6624) is a humanized monoclonal antibody designed for the treatment of fibrosis. It binds to LOXL2 and acts as an immunomodulator. In January 2016, Gilead Sciences terminated its Phase 2 clinical study in patients with idiopathic pulmonary fibrosis (IPF) due to lack of efficacy.
ApplicationFCM, IP, ELISA, Neut, FuncS
RemarksThis product is for research use only.

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