Anti-Human CD221 Recombinant Antibody(Cixutumumab)
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产品编号
YR1191
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别名
科研级 Cixutumumab ( 西妥木单抗 ), Anti-CD221 Recombinant Antibody, Research Grade Cixutumumab
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规格
- 1mg
- 5mg
Alias | 科研级 Cixutumumab ( 西妥木单抗 ), Anti-CD221 Recombinant Antibody, Research Grade Cixutumumab |
Catalog Number | YR1191 |
Molecular Name | Cixutumumab |
Size | 1mg, 5mg |
Clonity | Monoclonal |
Purity | >95% as determined by SDS-PAGE |
Concentration | 1mg/ml |
Antibody Isotype | IgG1 Lambda |
Formulation | PBS, pH7.5 |
Background | Cixutumumab (IMC-A12) is a human monoclonal antibody for the treatment of solid tumors. It is a fully human IgG1 monoclonal antibody directed against the human insulin-like growth factor-1 receptor (IGF-1R) with potential antineoplastic activity. Cixutumumab selectively binds to membrane-bound IGF-1R, thereby preventing the binding of the ligand IGF-1 and subsequent activation of PI3K/AKT signaling pathway. |
CAS Number | 947687-12-9 |
Application | IF, IP, Neut, FuncS, ELISA, FCM |
Storage Condition | It is recommended to aliquote and store at -20°C for long term storage. Avoid repeated freezing and thawing cycles. |
Remarks | This product is for research use only. |
Shipping Condition | Shipped on ice packs. |
Target | CD221[Homo sapiens] |