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Anti-Human CD221 Recombinant Antibody(Cixutumumab)

Anti-Human CD221 Recombinant Antibody(Cixutumumab)

产品编号

YR1191

别名

科研级 Cixutumumab ( 西妥木单抗 ), Anti-CD221 Recombinant Antibody, Research Grade Cixutumumab

规格
  • 1mg
  • 5mg
产品介绍
Alias科研级 Cixutumumab ( 西妥木单抗 ), Anti-CD221 Recombinant Antibody, Research Grade Cixutumumab
Catalog NumberYR1191
Molecular NameCixutumumab
Size1mg, 5mg
ClonityMonoclonal
Purity>95% as determined by SDS-PAGE
Concentration1mg/ml
Antibody IsotypeIgG1 Lambda
FormulationPBS, pH7.5
BackgroundCixutumumab (IMC-A12) is a human monoclonal antibody for the treatment of solid tumors. It is a fully human IgG1 monoclonal antibody directed against the human insulin-like growth factor-1 receptor (IGF-1R) with potential antineoplastic activity. Cixutumumab selectively binds to membrane-bound IGF-1R, thereby preventing the binding of the ligand IGF-1 and subsequent activation of PI3K/AKT signaling pathway.
CAS Number947687-12-9
ApplicationIF, IP, Neut, FuncS, ELISA, FCM
Storage ConditionIt is recommended to aliquote and store at -20°C for long term storage. Avoid repeated freezing and thawing cycles.
RemarksThis product is for research use only.
Shipping ConditionShipped on ice packs.
TargetCD221[Homo sapiens]

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