Recombinant Mouse TIM-3/Havcr2 Protein, His Tag

产品编号

MOP2296

别名

Tim3, TIM 3, Timd3, hepatitis A virus cellular receptor 2

规格

50ug
100ug

DATASHEET COA

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产品介绍

Alias	Tim3, TIM 3, Timd3, hepatitis A virus cellular receptor 2
Catalog Number	MOP2296
Molecular Name	Havcr2
Species	Mouse
Host	Mammalian cells
Size	50ug, 100ug
Protein Family	Other protein
Purity	≥90% as determined by SDS-PAGE
Concentration	联系销售经理获得最新批次的浓度
Purification	Affinity Purification
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Formulation	PBS
Background	Hepatitis A virus cellular receptor 2 (HAVCR2), formerly known as T cell immunoglobulin and mucin domain-3 (TIM-3), is a transmembrane glycoprotein expressed on the surface of terminally differentiated Th1 cells but not on Th2 cells. It was the first surface molecule that specifically identifies Th1 cells in both mice and human. Recently, identification of Galectin-9 as a ligand for TIM-3 has established the TIM-3-Galectin-9 pathway as an important regulator of Th1 immunity and tolerance induction. Engagement of Tim-3 by its ligand galectin-9 negatively regulates IFNgamma secretion and influences the ability to induce T cell tolerance in both mice and man.
Cross-reactivity	No cross-reactivity with other antigens or proteins.
Predicted N Terminus	Leu 22
Storage Condition	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.
Molecular Weight	18.92 kDa
Note	仅供科研使用
Product Declaration	该产品仅供科研使用，不可直接用于人体或注射。
Temperature Range	Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -25℃. Avoid repeated freeze-thaw cycles.