Mouse CLEC-2 Protein, hFc Tag

产品编号

KMP3883

别名

C型凝集素样受体-2, CLEC-2 Protein, Mouse CLEC-2 Protein, hFc Tag

规格

50ug
100ug
200ug

DATASHEET COA

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产品介绍

Alias	C型凝集素样受体-2, CLEC-2 Protein, Mouse CLEC-2 Protein, hFc Tag
Catalog Number	KMP3883
Product Description	The Mouse CLEC-2 Protein(KMP3883) is produced in HEK293 Cells. A DNA sequence encoding the Mouse Clec1b (NP_064369.1) (Met53-Leu229) is expressed with the Fc region of human IgG1 at the N-terminus.
Molecular Name	CLEC-2
Species	Mouse
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>90% as determined by SDS-PAGE
Concentration	联系销售经理获得最新批次的浓度
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	CLEC1B, also known as CLEC2, is a C-type lectin-like receptor expressed in myeloid cells and NK cells. Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 and NKG2D, that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 acts as a receptor for the platelet-aggregating snake venom protein rhodocytin. Rhodocytin binding leads to tyrosine phosphorylation and this promotes the binding of spleen tyrosine kinase (Syk) and initiation of downstream tyrosine phosphorylation events and activation of PLC-gamma-2. CLEC2 contains 1 C-type lectin domain and is expressed preferentially in the liver. It acts as an attachment factor for human immunodeficiency virus type 1 (HIV-1) and facilitates its capture by platelets.
Cross-reactivity	No cross-reactivity with other antigens or proteins.
Predicted N Terminus	Met 53
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	49.1 kDa
Product Declaration	该产品仅供科研使用，不可直接用于人体或注射。
Temperature Range	Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -25℃. Avoid repeated freeze-thaw cycles.