Human LAG3 Protein, His Tag

产品编号

KMP3382

别名

淋巴细胞激活基因-3, Human LAG3 Protein, His Tag, LAG3

规格

50ug
100ug
200ug

DATASHEET COA

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产品介绍

Alias	淋巴细胞激活基因-3, Human LAG3 Protein, His Tag, LAG3
Catalog Number	KMP3382
Product Description	The Human LAG3 Protein(KMP3382) is produced in HEK293 Cells. The target gene encoding the human LAG3 (NP_002277.4) (Met1-Leu450) is expressed with a polyhistidine tag at the C-terminus.
Molecular Name	LAG3
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Concentration	联系销售经理获得最新批次的浓度
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfamily. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 contains 4 extracellular Ig-like domains and has a negative regulatory function in T cells. It also acts as a new marker of T cell-induced B cell activation. As a soluble molecule, LAG3 activates antigen-presenting cells through MHC class II signaling, leading to increased antigen-specific T-cell responses in vivo. Diseases associated with LAG3 include Smoldering Myeloma and Kyphoscoliotic Heart Disease.
Cross-reactivity	No cross-reactivity with other antigens or proteins.
Predicted N Terminus	Met
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	47.6 kDa
Product Declaration	该产品仅供科研使用，不可直接用于人体或注射。
Temperature Range	Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -25℃. Avoid repeated freeze-thaw cycles.