Human Nectin-2 Protein, hFc Tag, Avi Tag
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产品编号
KMP2445
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别名
粘连蛋白细胞粘附分子, Human Nectin-2 Protein, hFc Tag, Avi Tag, Nectin-2
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规格
- 50ug
- 100ug
- 200ug
产品介绍
| Alias | 粘连蛋白细胞粘附分子, Human Nectin-2 Protein, hFc Tag, Avi Tag, Nectin-2 |
| Catalog Number | KMP2445 |
| Product Description | The Human Nectin-2 Protein(KMP2445) is produced in HEK293 Cells. The target gene encoding the human NECTIN2 (NP_002847.1)(Met1-Leu360) is expressed with a c-terminal Avi tagged Fc region of human IgG1 at the C-terminus (Fc-Avi). The expressed protein is biotinylated in vivo by the Biotin-Protein ligase (BirA enzyme) which is co-expressed. |
| Molecular Name | Nectin-2 |
| Species | Human |
| Host | HEK293 Cells |
| Size | 50ug, 100ug, 200ug |
| Purity | >95% as determined by SDS-PAGE |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | PBS, pH7.4 |
| Background | Cluster of Differentiation 112 (CD112), also known as poliovirus receptor related protein 2 (PVRL2 or PRR2), is a single-pass type I transmembrane glycoprotein belonging to the Immunoglobulin superfamily. CD112 protein also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and thus is involved in cell to cell spreading of these viruses. CD112 protein has been identified as the ligand for DNAM-1 (CD226), and the interaction of CD226/CD112 protein can induce NK cell- and CD8+ T cell-mediated cytotoxicity and cytokine secretion. CD112 has been regarded as a critical component in allergic reactions, and accordingly may function as a novel target for anti-allergic therapy. |
| Cross-reactivity | No cross-reactivity with other antigens or proteins. |
| Predicted N Terminus | Met |
| Reconstitution | Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Remarks | 收到产品后请立即按保存条件储存；使用前短暂离心，使内容物集中于管底；避免反复冻融。 |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
| Molecular Weight | 64.08 kDa |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
| Temperature Range | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -25℃. Avoid repeated freeze-thaw cycles. |
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