Human HAVCR2 Protein, His Tag

产品编号

KMP2404

别名

甲型肝炎病毒细胞受体 2, Hepatitis A virus cellular receptor 2, HAVCR2

规格

50ug
100ug
200ug

DATASHEET COA

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产品介绍

Alias	甲型肝炎病毒细胞受体 2, Hepatitis A virus cellular receptor 2, HAVCR2
Catalog Number	KMP2404
Product Description	The Human HAVCR2 Protein(KMP2404) is produced in HEK293 Cells and the target gene encoding Ser22-Arg200 is expressed with a 6His tag at the C-terminus.
Molecular Name	HAVCR2
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Concentration	联系销售经理获得最新批次的浓度
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	20mM PB, 150mM NaCl, pH7.4
Background	T-Cell Membrane Protein 3(TIM3) is a single-pass type I membrane protein that belongs to the TIM family of immunoglobulin superfamily. TIM3 includes a signal sequence(aa 1-21), an extracellular region(aa 22-202) with one Ig-like V-type domain, a transmembrane segment(aa 203-223), and a cytoplasmic domain(aa 224 - 301). TIM3 regulates macrophage activation, inhibits T-helper type 1 lymphocyte(Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. It may be also involved in T-cell homing and as a receptor for LGALS9.
Cross-reactivity	No cross-reactivity with other antigens or proteins.
Predicted Molecular Weight	20.7 kDa
Predicted N Terminus	Met
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.
Uniprot ID	E5RHN3#structure
Product Declaration	该产品仅供科研使用，不可直接用于人体或注射。
Temperature Range	Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -25℃. Avoid repeated freeze-thaw cycles.