Macaca Fascicularis CD223 Protein, His Tag
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产品编号
KMP2389
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别名
淋巴细胞活化基因3, Lymphocyte activation gene 3 protein, LAG3
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规格
- 50ug
- 100ug
- 200ug
产品介绍
| Alias | 淋巴细胞活化基因3, Lymphocyte activation gene 3 protein, LAG3 |
| Catalog Number | KMP2389 |
| Product Description | The Macaca Fascicularis CD233 Protein(KMP2389) is produced in HEK293 Cells and the target gene encoding Ala18-Leu450 is expressed with a 8His tag at the N-terminus. |
| Molecular Name | CD223 |
| Species | Macaca Fascicularis |
| Host | HEK293 Cells |
| Size | 50ug, 100ug, 200ug |
| Purity | >90% as determined by SDS-PAGE |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | PBS, pH7.4 |
| Background | Lymphocyte Activating 3(LAG3) belongs to immunoglobulin(Ig) superfamily, Macaca fascicularis LAG3 cDNA encodes 533 amino acids(aa) that include a 17 aa signal sequence, a 451 aa extracellular domain(ECD) with two Ig-like domains, a transmembrane region and a highly charged cytoplasmic region. LAG3's main ligand is MHC class II, to which it binds with higher affinity than CD4.The protein negatively regulates cellular proliferation, activation, and homeostasis of T cells, in a similar fashion to CTLA-4 and PD-1 and has been reported to play a role in Treg suppressive function. |
| Cross-reactivity | No cross-reactivity with other antigens or proteins. |
| Predicted Molecular Weight | 48.18 kDa |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
| Temperature Range | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -25℃. Avoid repeated freeze-thaw cycles. |
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