Human HAVCR2 Protein, Fc Tag, Avi Tag
-
产品编号
KMP2301
-
别名
甲型肝炎病毒细胞受体 2, Hepatitis A virus cellular receptor 2, HAVCR2
-
规格
- 50ug
- 100ug
- 200ug
产品介绍
| Alias | 甲型肝炎病毒细胞受体 2, Hepatitis A virus cellular receptor 2, HAVCR2 |
| Catalog Number | KMP2301 |
| Product Description | The Human HAVCR2 Protein(KMP2301) is produced in HEK293 Cells and the target gene encoding Ser22-Arg200 is expressed with a Fc, Avi tag at the C-terminus. |
| Molecular Name | HAVCR2 |
| Species | Human |
| Host | HEK293 Cells |
| Size | 50ug, 100ug, 200ug |
| Purity | >85% as determined by SDS-PAGE |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | PBS, pH7.4 |
| Background | Hepatitis A virus cellular receptor 2(HAVCR2) is a single-pass type I membrane protein and it contains 1 Ig-like V-type(immunoglobulin-like) domain. The protein belongs to the immunoglobulin superfamily, and TIM family of proteins. The protein regulates macrophage activation. It inhibits T-helper type 1 lymphocyte(Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. It may be also involved in T-cell homing and it is receptor for LGALS9. CD4(MIM 186940)-positive T helper lymphocytes can be divided into types 1(Th1) and 2(Th2) on the basis of their cytokine secretion patterns. Th1 cells and their associated cytokines are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. The 2 types of cells also cross-regulate the functions of the other. TIM3 is a Th1-specific cell surface protein that regulates macrophage activation and enhances the severity of experimental autoimmune encephalomyelitis in mice. |
| Cross-reactivity | No cross-reactivity with other antigens or proteins. |
| Predicted Molecular Weight | 19.87 kDa |
| Predicted N Terminus | Met |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form. |
| Uniprot ID | A0A8Q3SJ74 |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
| Temperature Range | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -25℃. Avoid repeated freeze-thaw cycles. |
- 联系我们
- 电话：400-621-6806
- 手机：13116038708（微信）
- 邮箱：info@kmdbioscience.com
- 地址：天津市武清开发区和畅路6号10号厂房108室
-
销售微信
-
官方公众号
-
400-621-6806 -
3599163699 -
周一至周五 9:00-18:00 -
-
0
-
