Rat CD86 Protein, His Tag
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产品编号
KMP2296
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别名
T 淋巴细胞活化抗原 CD86, T-lymphocyte activation antigen CD86, CD86
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规格
- 50ug
- 100ug
- 200ug
| Alias | T 淋巴细胞活化抗原 CD86, T-lymphocyte activation antigen CD86, CD86 |
| Catalog Number | KMP2296 |
| Product Description | The Rat CD86 Protein(KMP2296) is produced in HEK293 Cells and the target gene encoding Vla29-Lys247 is expressed with a 6His tag at the C-terminus. |
| Molecular Name | CD86 |
| Species | Rat |
| Host | HEK293 Cells |
| Size | 50ug, 100ug, 200ug |
| Purity | >95% as determined by SDS-PAGE |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | PBS, pH7.4 |
| Background | T-lymphocyte activation antigen CD86(B7-2) is a glycosylated protein in the B7 family. B7 family members are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of immune tolerance. It is highly expressed on activated antigen presenting cells. CD86 involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. It may play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. It is expressed by activated B-lymphocytes and monocytes and promoted by MARCH8 and results in endocytosis and lysosomal degradation. |
| Cross-reactivity | No cross-reactivity with other antigens or proteins. |
| Predicted Molecular Weight | 25.87 kDa |
| Predicted N Terminus | Pro 30 |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form. |
| Uniprot ID | O35531 |
| Product Declaration | 该产品仅供科研使用,不可直接用于人体或注射。 |
| Temperature Range | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -25℃. Avoid repeated freeze-thaw cycles. |
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