Recombinant Human CD256/TNFSF13 Protein, His Tag

产品编号

KMH407

别名

APRIL, CD256, TALL2, ZTNF2, TALL 2, TNLG7B, TRDL 1, UNQ383/PRO715, TNF superfamily member 13

规格

50ug
100ug

DATASHEET COA

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产品介绍

Alias	APRIL, CD256, TALL2, ZTNF2, TALL 2, TNLG7B, TRDL 1, UNQ383/PRO715, TNF superfamily member 13
Catalog Number	KMH407
Molecular Name	TNFSF13
Species	Human
Host	Mammalian cells
Size	50ug, 100ug
Protein Family	CD molecule
Purity	≥90% as determined by SDS-PAGE
Concentration	联系销售经理获得最新批次的浓度
Purification	Affinity Purification
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Formulation	PBS
Background	APRIL is synthesized as a 32 kDa type II transmembrane protein which is cleaved by furin in the Golgi to release a 17 kDa soluble molecule. Human APRIL shares 85% aa sequence identity with mouse and rat APRIL. Among TNF superfamily ligands, BAFF shows the greatest sequence homology with APRIL, and the two proteins exhibit overlapping biological activities. Both APRIL and BAFF bind and signal through the TNF superfamily receptors TACI and BCMA, and BAFF additionally functions through BAFF R. APRIL can form bioactive heterotrimers with BAFF, and these circulate in the serum of patients with rheumatic immune disorders. A bioactive protein known as TWEPRIL consists of the intracellular domain, transmembrane segment, and stalk region of TWEAK fused to the TNF homology domain of APRIL. TWEPRIL is expressed in monocytes and activated T cells, and in contrast to APRIL, it is presented on the cell surface.
Cross-reactivity	No cross-reactivity with other antigens or proteins.
Storage Condition	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.
Molecular Weight	16.06 kDa
Note	仅供科研使用
Product Declaration	该产品仅供科研使用，不可直接用于人体或注射。
Temperature Range	Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -25℃. Avoid repeated freeze-thaw cycles.