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Rat Erythropoietin Protein, His Tag
Rat Erythropoietin Protein, His Tag

Rat Erythropoietin Protein, His Tag

产品编号

KMP4191

别名

人促红细胞生成素, Erythropoietin Protein, Rat Erythropoietin Protein, His Tag

目录价格

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规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias人促红细胞生成素, Erythropoietin Protein, Rat Erythropoietin Protein, His Tag
Catalog NumberKMP4191
Product DescriptionThe Rat Erythropoietin Protein(KMP4191) is produced in Insect Cells. A DNA sequence encoding the rat EPO (P29676-1) (Met 1-Arg 192) is fused with a polyhistidine tag at the C-terminus.
Molecular NameErythropoietin
SpeciesRat
HostInsect Cells
Size50ug, 100ug, 200ug
Protein FamilyOther protein
Purity>90% as determined by SDS-PAGE
Concentration联系销售经理获得最新批次的浓度
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
Formulation20mM Tris, 500mM NaCl, pH7.4
BackgroundErythropoietin is a member of the EPO/TPO family. It is a secreted, glycosylated cytokine composed of four alpha helical bundles. Erythropoietin can be found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. It also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types. Erythropoietin is the principal hormone involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass. It is produced by kidney or liver of adult mammals and by liver of fetal or neonatal mammals. Genetic variation in erythropoietin is associated with susceptbility to microvascular complications of diabetes type 2. These are pathological conditions that develop in numerous tissues and organs as a consequence of diabetes mellitus. They include diabetic retinopathy, diabetic nephropathy leading to end-stage renal disease, and diabetic neuropathy. Diabetic retinopathy remains the major cause of new-onset blindness among diabetic adults. It is characterized by vascular permeability and increased tissue ischemia and angiogenesis. It has a longer circulating half-life in vivo. Erythropoietin is being much misused as a performance-enhancing drug in endurance athletes.
ApplicationWB, ELISA
Recommended DilutionELISA: 1:100-1:1000
Cross-reactivityNo cross-reactivity with other antigens or proteins.
Predicted Molecular Weight20 kDa
Predicted N TerminusMet
ReconstitutionNot applicable. The product is supplied as a ready-to-use liquid formulation.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Remarks收到产品后请立即按保存条件储存;使用前短暂离心,使内容物集中于管底;避免反复冻融。
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
StabilitySamples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Molecular Weight20 kDa
Cross-reactivityNo cross-reactivity with other antigens or proteins.
Note仅供科研使用
ELISA IC50(ppb)≥ 1:1000
FunctionErythropoietin is a member of the EPO/TPO family. It is a secreted, glycosylated cytokine composed of four alpha helical bundles. Erythropoietin can be found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. It also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types. Erythropoietin is the principal hormone involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass. It is produced by kidney or liver of adult mammals and by liver of fetal or neonatal mammals. Genetic variation in erythropoietin is associated with susceptbility to microvascular complications of diabetes type 2. These are pathological conditions that develop in numerous tissues and organs as a consequence of diabetes mellitus. They include diabetic retinopathy, diabetic nephropathy leading to end-stage renal disease, and diabetic neuropathy. Diabetic retinopathy remains the major cause of new-onset blindness among diabetic adults. It is characterized by vascular permeability and increased tissue ischemia and angiogenesis. It has a longer circulating half-life in vivo. Erythropoietin is being much misused as a performance-enhancing drug in endurance athletes.
Product Declaration该产品仅供科研使用,不可直接用于人体或注射。
Temperature Range-20℃ ~ -80℃
Solubility产品为即用型液体,无需复溶。
AppearanceLiquid
Product Full NameRat Erythropoietin Protein
Preservative Solution20mM Tris, 500mM NaCl, pH7.4
TargetErythropoietin

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