Recombinant Human HMGB1 Protein, His Tag
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产品编号
KMH574
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别名
HMG1, HMG3, HMG 1, SBP 1, high mobility group box 1
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目录价格
联系客服获取报价RMB
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规格
- 50ug
- 100ug
产品介绍
| Alias | HMG1, HMG3, HMG 1, SBP 1, high mobility group box 1 |
| Catalog Number | KMH574 |
| Molecular Name | HMGB1 |
| Species | Human |
| Host | Mammalian cells |
| Size | 50ug, 100ug |
| Protein Family | Other protein |
| Purity | ≥90% as determined by SDS-PAGE |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purification | Affinity Purification |
| Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
| Formulation | Supplied as solution form in 50mM Tris HCl pH 7, 150mM NaCl, 1mM EDTA./Lyophilized from 50mM Tris HCl pH 7, 150mM NaCl, 1mM EDTA. |
| Background | High-mobility group box 1 protein (HMGB1), previously known as HMG-1 or amphoterin, is a member of the high mobility group box family of non-histone chromosomal proteins. Human HMGB1 is expressed as a 3 kDa, 215 amino acid (aa) single chain polypeptide containing three domains: two N-terminal globular, 7 aa positively charged DNA-binding domains (HMG boxes A and B), and a negatively charged 3 aa C-terminal region that contains only Asp and Glu.4, 5 Residues 27 - 43 and 178 - 184 contain a NLS. Posttranslational modifications of the molecule have been reported, with acetylation occurring on as many as 17 lysine residues. |
| Application | WB, ELISA |
| Recommended Dilution | ELISA: 1:100-1:1000 |
| Cross-reactivity | No cross-reactivity with other antigens or proteins. |
| Predicted Molecular Weight | 26.97 kDa |
| Predicted N Terminus | Met |
| Reconstitution | Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. |
| Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
| Remarks | 收到产品后请立即按保存条件储存；使用前短暂离心，使内容物集中于管底；避免反复冻融。 |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Stability | Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
| Molecular Weight | 26.97 kDa |
| Cross-reactivity | No cross-reactivity with other antigens or proteins. |
| Uniprot ID | P09429 |
| Note | 仅供科研使用 |
| ELISA IC50(ppb) | ≥ 1:1000 |
| Function | High-mobility group box 1 protein (HMGB1), previously known as HMG-1 or amphoterin, is a member of the high mobility group box family of non-histone chromosomal proteins. Human HMGB1 is expressed as a 3 kDa, 215 amino acid (aa) single chain polypeptide containing three domains: two N-terminal globular, 7 aa positively charged DNA-binding domains (HMG boxes A and B), and a negatively charged 3 aa C-terminal region that contains only Asp and Glu.4, 5 Residues 27 - 43 and 178 - 184 contain a NLS. Posttranslational modifications of the molecule have been reported, with acetylation occurring on as many as 17 lysine residues. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
| Temperature Range | -20℃ ~ -80℃ |
| Solubility | 复溶后易溶于无菌去离子水或PBS缓冲液（pH 7.4）。 |
| Appearance | Lyophilized powder |
| Product Full Name | Recombinant Human HMGB1 Protein |
| Preservative Solution | Supplied as solution form in 50mM Tris HCl pH 7, 150mM NaCl, 1mM EDTA./Lyophilized from 50mM Tris HCl pH 7, 150mM NaCl, 1mM EDTA. |
| Target | HMGB1 |
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