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Recombinant Human CDKN1B Protein, His Tag
Recombinant Human CDKN1B Protein, His Tag

Recombinant Human CDKN1B Protein, His Tag

产品编号

KMH854

别名

KIP1, MEN4, CDKN4, MEN1B, P27KIP1, cyclin dependent kinase inhibitor 1B

规格
  • 50ug
  • 100ug
产品介绍
AliasKIP1, MEN4, CDKN4, MEN1B, P27KIP1, cyclin dependent kinase inhibitor 1B
Catalog NumberKMH854
Molecular NameCDKN1B
SpeciesHuman
HostE. coli
Size50ug, 100ug
Protein FamilyOther protein
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
EndotoxinPlease contact our customer service for more information.
FormulationPBS
BackgroundKIP1 (cyclin-dependent kinase inhibitor 1B) is a kinesin-related motor protein required for mitotic spindle assembly and chromosome segregation. Many tumorigenic processes modulate cell-cycle progression by regulating the levels of the cyclin-dependent kinase inhibitor KIP1. KIP1 binds to and inhibits cyclinE-Cdk2 complex, cyclinA-CDK2 and cyclinD1-CDK4. The phosphorylation- and ubiquitination-dependent proteolysis of KIP1 is implicated in control of the G1-S transition in the cell cycle. KIP1 is critical for retinoblastoma protein (Rb)-induced cellular proliferative senescence.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight21.78 kDa
Note仅供科研使用

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