| Alias | IL-4Rα和IL-13Rα1的异二聚体蛋白, Human IL-4Rα & IL-13Rα1 Heterodimer Protein, His Tag, IL-4Rα & IL-13Rα1 Heterodimer |
| Catalog Number | KMP3565 |
| Product Description | The Human IL-4Rα & IL-13Rα1 Heterodimer Protein(KMP3565) is produced in HEK293 Cells. The target gene encoding the human IL4R (NP_000409.1)(Met1-His232) is expressed with a polyhistidine tag at the C-terminus, constructed the plasmid 1; The target gene encoding the human IL13RA1 (NP_001551.1) (Met1-Thr343 is expressed with a polyhistidine tag at the C-terminus, constructed the plasmid 2. The two plasmids are co-expressed and the IL4R & IL13RA1 heterodimer is purified. |
| Molecular Name | IL-4Rα & IL-13Rα1 Heterodimer |
| Species | Human |
| Host | HEK293 Cells |
| Size | 50ug, 100ug, 200ug |
| Protein Family | Other protein |
| Purity | >95% as determined by SDS-PAGE |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | PBS, pH7.4 |
| Background | IL4R (Interleukin 4 Receptor) is a Protein Coding gene. Diseases associated with IL4R include Ige Responsiveness, Atopic and Human Immunodeficiency Virus Type 1. Among its related pathways are TGF-Beta Pathway and Akt Signaling. Gene Ontology (GO) annotations related to this gene include obsolete signal transducer activity, downstream of receptor and interleukin-4 receptor activity. An important paralog of this gene is CSF2RB. IL13RA1 (Interleukin 13 Receptor Subunit Alpha 1) is a Protein Coding gene. Diseases associated with IL13RA1 include Monofixation Syndrome and Asthma. Among its related pathways are Akt Signaling and Cytokine Signaling in Immune system. Gene Ontology (GO) annotations related to this gene include interleukin-13 receptor activity. An important paralog of this gene is OSMR. |
| Application | WB, ELISA |
| Recommended Dilution | ELISA: 1:100-1:1000 |
| Cross-reactivity | No cross-reactivity with other antigens or proteins. |
| Predicted Molecular Weight | 63.52 kDa |
| Predicted N Terminus | Met |
| Reconstitution | Not applicable. The product is supplied as a ready-to-use liquid formulation. |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Remarks | 收到产品后请立即按保存条件储存；使用前短暂离心，使内容物集中于管底；避免反复冻融。 |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
| Stability | Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
| Molecular Weight | 63.52 kDa |
| Cross-reactivity | No cross-reactivity with other antigens or proteins. |
| Note | 仅供科研使用 |
| ELISA IC50(ppb) | ≥ 1:1000 |
| Function | IL4R (Interleukin 4 Receptor) is a Protein Coding gene. Diseases associated with IL4R include Ige Responsiveness, Atopic and Human Immunodeficiency Virus Type 1. Among its related pathways are TGF-Beta Pathway and Akt Signaling. Gene Ontology (GO) annotations related to this gene include obsolete signal transducer activity, downstream of receptor and interleukin-4 receptor activity. An important paralog of this gene is CSF2RB. IL13RA1 (Interleukin 13 Receptor Subunit Alpha 1) is a Protein Coding gene. Diseases associated with IL13RA1 include Monofixation Syndrome and Asthma. Among its related pathways are Akt Signaling and Cytokine Signaling in Immune system. Gene Ontology (GO) annotations related to this gene include interleukin-13 receptor activity. An important paralog of this gene is OSMR. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
| Temperature Range | -20℃ ~ -80℃ |
| Solubility | 产品为即用型液体，无需复溶。 |
| Appearance | Liquid |
| Product Full Name | Human IL-4Rα & IL-13Rα1 Heterodimer Protein |
| Preservative Solution | PBS, pH7.4 |
| Usage Method | 冻干粉请按“复溶”说明用无菌去离子水复溶后使用，液体产品可直接使用；具体工作浓度请参考“推荐稀释比例”。 |
| Target | IL-4Rα & IL-13Rα1 Heterodimer |
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