Human LRRTM2 Protein, hFc Tag
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产品编号
KMP3273
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别名
富亮氨酸重复跨膜神经元, Human LRRTM2 Protein, hFc Tag, LRRTM2
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目录价格
联系客服获取报价RMB
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规格
- 50ug
- 100ug
- 200ug
产品介绍
| Alias | 富亮氨酸重复跨膜神经元, Human LRRTM2 Protein, hFc Tag, LRRTM2 |
| Catalog Number | KMP3273 |
| Product Description | The Human LRRTM2 Protein(KMP3273) is produced in HEK293 Cells. The target gene encoding the human LRRTM2 (NP_056379.1) (Met1-Arg422) is expressed with the Fc region of human IgG1 at the C-terminus. |
| Molecular Name | LRRTM2 |
| Species | Human |
| Host | HEK293 Cells |
| Size | 50ug, 100ug, 200ug |
| Protein Family | Other protein |
| Purity | >90% as determined by SDS-PAGE |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | PBS, pH7.4 |
| Background | LRRTM2 (Leucine-Rich Repeat Transmembrane Neuronal 2) is a Protein Coding gene. LRRTM2 belongs to the LRRTM family and is a key regulator of excitatory synapse development and function. It localizes to excitatory synapses in transfected hippocampal neurons, and shRNA-mediated knockdown of LRRTM2 leads to a decrease in excitatory synapses without affecting inhibitory synapses. LRRTM2 interacts with PSD-95 and regulates surface expression of AMPA receptors, and lentivirus-mediated knockdown of LRRTM2 in vivo decreases the strength of evoked excitatory synaptic currents. LRRTM2 induces only excitatory synapses, and that it also acts to induce synapses in transfected neurons similarly to neuroligin-1. Diseases associated with LRRTM2 include Tarp Syndrome and Histrionic Personality Disorder. |
| Application | WB, ELISA |
| Recommended Dilution | ELISA: 1:100-1:1000 |
| Cross-reactivity | No cross-reactivity with other antigens or proteins. |
| Predicted Molecular Weight | 71.2 kDa |
| Predicted N Terminus | Met |
| Reconstitution | Not applicable. The product is supplied as a ready-to-use liquid formulation. |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Remarks | 收到产品后请立即按保存条件储存；使用前短暂离心，使内容物集中于管底；避免反复冻融。 |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
| Stability | Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
| Molecular Weight | 71.2 kDa |
| Cross-reactivity | No cross-reactivity with other antigens or proteins. |
| Note | 仅供科研使用 |
| ELISA IC50(ppb) | ≥ 1:1000 |
| Function | LRRTM2 (Leucine-Rich Repeat Transmembrane Neuronal 2) is a Protein Coding gene. LRRTM2 belongs to the LRRTM family and is a key regulator of excitatory synapse development and function. It localizes to excitatory synapses in transfected hippocampal neurons, and shRNA-mediated knockdown of LRRTM2 leads to a decrease in excitatory synapses without affecting inhibitory synapses. LRRTM2 interacts with PSD-95 and regulates surface expression of AMPA receptors, and lentivirus-mediated knockdown of LRRTM2 in vivo decreases the strength of evoked excitatory synaptic currents. LRRTM2 induces only excitatory synapses, and that it also acts to induce synapses in transfected neurons similarly to neuroligin-1. Diseases associated with LRRTM2 include Tarp Syndrome and Histrionic Personality Disorder. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
| Temperature Range | -20℃ ~ -80℃ |
| Solubility | 产品为即用型液体，无需复溶。 |
| Appearance | Liquid |
| Product Full Name | Human LRRTM2 Protein |
| Preservative Solution | PBS, pH7.4 |
| Usage Method | 冻干粉请按“复溶”说明用无菌去离子水复溶后使用，液体产品可直接使用；具体工作浓度请参考“推荐稀释比例”。 |
| Target | LRRTM2 |
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