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Recombinant Human SPARC Protein, His Tag
Recombinant Human SPARC Protein, His Tag

Recombinant Human SPARC Protein, His Tag

产品编号

KMH1741

别名

ON, ONT, OI17, BM 40, secreted protein acidic and cysteine rich

规格
  • 50ug
  • 100ug
产品介绍
AliasON, ONT, OI17, BM 40, secreted protein acidic and cysteine rich
Catalog NumberKMH1741
Molecular NameSPARC
SpeciesHuman
HostMammalian cells
Size50ug, 100ug
Protein FamilyOther protein
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
Endotoxin< 1.0 EU per ug of the protein as determined by the LAL method.
FormulationPBS
BackgroundSPARC, an acronym for secreted protein, acidic and rich in cysteine, is also known as osteonectin or BM-4. It is the founding member of a family of secreted matricellular proteins with similar domain structure. The 33 amino acid, 43 kDa protein contains a 17 aa signal sequence, an N-terminal acidic region that binds calcium, a follistatin domain containing Kazal-like sequences, and a C-terminal extracellular calcium (EC) binding domain with two EF-hand motifs. SPARC is produced by fibroblasts, capillary endothelial cells, platelets and macrophages, especially in areas of tissue morphogenesis and remodeling. SPARC shows context-specific effects, but generally inhibits adhesion, spreading and proliferation, and promotes collagen matrix formation.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight31.46 kDa
Note仅供科研使用

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