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生长因子与受体

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Recombinant Human HPGD Protein, His Tag

Recombinant Human HPGD Protein, His Tag

Recombinant Human HPGD Protein, His Tag

产品编号

KMH1223

别名

PGDH, PGDH1, PHOAR1, 15 PGDH, SDR36C1, 15 hydroxyprostaglandin dehydrogenase

规格

50ug
100ug

DATASHEET COA

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产品介绍

Alias	PGDH, PGDH1, PHOAR1, 15 PGDH, SDR36C1, 15 hydroxyprostaglandin dehydrogenase
Catalog Number	KMH1223
Molecular Name	HPGD
Species	Human
Host	Mammalian cells
Size	50ug, 100ug
Protein Family	Other protein
Purity	≥90% as determined by SDS-PAGE
Purification	Affinity Purification
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Formulation	PBS
Background	NAD+-dependent 15-hydroxy prostaglandin dehydrogenase (15-PGDH) catalyzes the oxidation of PGs to 15-keto metabolites that have greatly reduced biological activity. Human NAD+-dependent 15-PGDH is a 266 amino acid protein with a molecular weight of 29 kDa and is expressed in multiple tissues including lung, placenta, and kidney. The enzyme belongs to a large family of short-chain alcohol dehydrogenases, which exhibit amino acid identity ranging from 15-3%. Recent studies indicate 15-PGDH may play a role as a tumor suppressor. Studies have shown an inverse correlation between 15-PGDH expression and cell proliferation in colon, breast, and thyroid cells. 15-PGDH specific activity was determined using PGE2 as the substrate and NAD+ as the cofactor and was calculated after subtracting the mass contribution form the GST tag.
Storage Condition	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.
Molecular Weight	29.26 kDa
Note	仅供科研使用

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