Recombinant Human Sonic Hedgehog (C24II), N-Terminus Protein

产品编号

KRP693

别名

SHH(C24II)蛋白,Sonic hedgehog protein Protein, HHG1 Protein, HLP3 Protein, HPE3 Protein

规格

100ug
500ug
1mg

DATASHEET COA

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产品介绍

Alias	SHH(C24II)蛋白,Sonic hedgehog protein Protein, HHG1 Protein, HLP3 Protein, HPE3 Protein
Catalog Number	KRP693
Molecular Name	SHH
Species	Human
Host	E.coli
Size	100ug,500ug,1mg
Purity	>97%, determined by SDS-PAGE.
Concentration	联系销售经理获得最新批次的浓度
Purification	Affinity Purification
Endotoxin	<0.01 EU/μg, determined by LAL method.
Background	这是SHH蛋白的一种特定变体（C24II突变型，通常指第24位半胱氨酸被异亮氨酸取代），该突变可能影响其修饰、加工或信号活性，常被用作研究刺猬信号通路特定方面的工具。
Application	WB, ELISA
Predicted Molecular Weight	20 kDa
Reconstitution	It is recommended that the lyophilized human Sonic Hedgehog (C24II), N-Terminus protein be dissolved in PBS at a concentration of 100-200 μg/mL for further dilution as the working concentration.
Storage Condition	Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.
Stability	Repeated freezing and thawing is not recommended.
Molecular Weight	22 kDa
Uniprot ID	Q15465
References	1. Briscoe, J. and P.P. Therond (2013) Mol. Cell. Biol. 14:416. 2. Aviles, E.C. et al. (2013) Front. Cell. Neurosci. 7:86. 3. Xie, J. et al. (2013) OncoTargets Ther. 6:1425. 4. Marigo, V. et al. (1995) Genomics 28:44. 5. Zeng, X. et al. (2001) Nature 411:716. 6. Feng, J. et al. (2004) Development 131:4357. 7. Goetz, J.A. et al. (2006) J. Biol. Chem. 281:4087. 8. Pepinsky, R.B. et al. (1998) J. Biol. Chem. 273:14037. 9. Chen, M.-H. et al. (2004) Genes Dev. 18:641. 10. Etheridge, L.A. et al. (2010) Development 137:133. 11. Jakobs, P. et al. (2014) J. Cell Sci. 127:1726. 12. Dierker, T. et al. (2009) J. Biol. Chem. 284:8013. 13. Lewis, P.M. et al. (2001) Cell 105:599. 14. Carpenter, D. et al. (1998) Proc. Natl. Acad. Sci. USA 95:13630. 15. Filmus, J. and M. Capurro (2014) Matrix Biol. 35:248. 16. Chuang, P.-T. and A.P. McMahon (1999) Nature 397:617.
Function	重组人音猬因子（C24II）N端活性片段，是具有特定修饰的高活性信号蛋白。适用于发育信号通路研究、神经干细胞定向分化及组织工程应用。
Product Declaration	该产品仅供科研使用，不可直接用于人体或注射。
Temperature Range	Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -37℃. Avoid repeated freeze-thaw cycles.
Product Full Name	Recombinant Human Sonic Hedgehog (C24II), N-Terminus Protein
Target	Sonic Hedgehog (C24II), N-Terminus