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Human MIP-5 Protein, His Tag
Human MIP-5 Protein, His Tag

Human MIP-5 Protein, His Tag

产品编号

KMP2777

别名

巨噬细胞炎症蛋白, Human MIP-5 Protein, His Tag, MIP-5

目录价格

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规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias巨噬细胞炎症蛋白, Human MIP-5 Protein, His Tag, MIP-5
Catalog NumberKMP2777
Product DescriptionThe Human MIP-5 Protein(KMP2777) is produced in E. coli. The target gene encoding the mature form of human CCL15 (Q16663-1) (Gln 22-Ile 113) is expressed, with a polyHistide tag at the C-terminus.
Molecular NameMIP-5
SpeciesHuman
HostE. coli
Size50ug, 100ug, 200ug
Protein FamilyOther protein
Purity>95% as determined by SDS-PAGE
Concentration联系销售经理获得最新批次的浓度
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundChemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling the migration of cells during normal processes of tissue maintenance and development. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands-1 to 28. Chemokine ligand 15 (CCL15), also known as leukotactin-1, MIP5, MIP1 and HCC-2, is a small cytokine belonging to the C-C chemokine family. CCL15 is prevantly expressed in liver, small intestine, colon, and in certain leukocytes and macrophages of the lung. It is chemotactic for neutrophils, monocytes, and lymphocytes and elicits its effects by binding to cell surface chemokine receptors like CCR1 and CCR3.
ApplicationWB, ELISA
Recommended DilutionELISA: 1:100-1:1000
Cross-reactivityNo cross-reactivity with other antigens or proteins.
Predicted Molecular Weight11.7 kDa
Predicted N TerminusGln 22
ReconstitutionNot applicable. The product is supplied as a ready-to-use liquid formulation.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Remarks收到产品后请立即按保存条件储存;使用前短暂离心,使内容物集中于管底;避免反复冻融。
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
StabilitySamples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Molecular Weight11.7 kDa
Cross-reactivityNo cross-reactivity with other antigens or proteins.
Note仅供科研使用
ELISA IC50(ppb)≥ 1:1000
FunctionChemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling the migration of cells during normal processes of tissue maintenance and development. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands-1 to 28. Chemokine ligand 15 (CCL15), also known as leukotactin-1, MIP5, MIP1 and HCC-2, is a small cytokine belonging to the C-C chemokine family. CCL15 is prevantly expressed in liver, small intestine, colon, and in certain leukocytes and macrophages of the lung. It is chemotactic for neutrophils, monocytes, and lymphocytes and elicits its effects by binding to cell surface chemokine receptors like CCR1 and CCR3.
Product Declaration该产品仅供科研使用,不可直接用于人体或注射。
Temperature Range-20℃ ~ -80℃
Solubility产品为即用型液体,无需复溶。
AppearanceLiquid
Product Full NameHuman MIP-5 Protein
Preservative SolutionPBS, pH7.4
Usage Method冻干粉请按“复溶”说明用无菌去离子水复溶后使用,液体产品可直接使用;具体工作浓度请参考“推荐稀释比例”。
TargetMIP-5

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