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Human CXCL14 Protein
Human CXCL14 Protein

Human CXCL14 Protein

产品编号

KMP2764

别名

CXC 基序趋化因子配体, Human CXCL14 Protein, CXCL14

目录价格

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规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
AliasCXC 基序趋化因子配体, Human CXCL14 Protein, CXCL14
Catalog NumberKMP2764
Product DescriptionThe Human CXCL14 Protein(KMP2764) is produced in E. coli. The target gene encoding human CXCL14 (O95715) (Ser35-Glu111) is expressed with a N-terminal Met.
Molecular NameCXCL14
SpeciesHuman
HostE. coli
Size50ug, 100ug, 200ug
Protein FamilyOther protein
Purity>90% as determined by SDS-PAGE
Concentration联系销售经理获得最新批次的浓度
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
Formulation100mM NaH2PO4, 1M NaCl, pH6.5
BackgroundCXCL14 is a CXC chemokine family that exhibits antimicrobial activity and contains an amphipathic cationic alpha-helical region in the C-terminus, a characteristic structure of antimicrobial peptides (AMPs). CXCL14 is involved in cell recruitment, migration, activation, and homing in liver diseases and have been shown to be upregulated during acute liver injury in animal models. The CXC chemokine ligand 14 (CXCL14) had been show highly expressed in tumor-associated stromal cells, promoting tumor cell growth, and invasion. The stimulation of dysregulated CXCL14 expression by P. gingivalis may help promote dysbiosis and the development of chronic periodontitis. The level of CXCL14 expression may be a valuable adjuvant parameter to predict the prognosis of patients with oral carcinoma and may be a potential therapeutic target.
ApplicationWB, ELISA
Recommended DilutionELISA: 1:100-1:1000
Cross-reactivityNo cross-reactivity with other antigens or proteins.
Predicted Molecular Weight9.4 kDa
Predicted N TerminusSer 35
ReconstitutionNot applicable. The product is supplied as a ready-to-use liquid formulation.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Remarks收到产品后请立即按保存条件储存;使用前短暂离心,使内容物集中于管底;避免反复冻融。
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
StabilitySamples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Molecular Weight9.4 kDa
Cross-reactivityNo cross-reactivity with other antigens or proteins.
Note仅供科研使用
ELISA IC50(ppb)≥ 1:1000
FunctionCXCL14 is a CXC chemokine family that exhibits antimicrobial activity and contains an amphipathic cationic alpha-helical region in the C-terminus, a characteristic structure of antimicrobial peptides (AMPs). CXCL14 is involved in cell recruitment, migration, activation, and homing in liver diseases and have been shown to be upregulated during acute liver injury in animal models. The CXC chemokine ligand 14 (CXCL14) had been show highly expressed in tumor-associated stromal cells, promoting tumor cell growth, and invasion. The stimulation of dysregulated CXCL14 expression by P. gingivalis may help promote dysbiosis and the development of chronic periodontitis. The level of CXCL14 expression may be a valuable adjuvant parameter to predict the prognosis of patients with oral carcinoma and may be a potential therapeutic target.
Product Declaration该产品仅供科研使用,不可直接用于人体或注射。
Temperature Range-20℃ ~ -80℃
Solubility产品为即用型液体,无需复溶。
AppearanceLiquid
Product Full NameHuman CXCL14 Protein
Preservative Solution100mM NaH2PO4, 1M NaCl, pH6.5
Usage Method冻干粉请按“复溶”说明用无菌去离子水复溶后使用,液体产品可直接使用;具体工作浓度请参考“推荐稀释比例”。
TargetCXCL14

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