| Alias | CD8A和CD8B的异二聚体蛋白, CD8A & CD8B Heterodimer Protein, Cynomolgus CD8A & CD8B Heterodimer Protein, Flag Tag, His Tag |
| Catalog Number | KMP3753 |
| Product Description | The Cynomolgus CD8A & CD8B Heterodimer Protein(KMP3753) is produced in HEK293 Cells. A DNA sequence encoding the Cynomolgus CD8A (XP_001092778.2) (Met42-Asp223) is fused with a flag tag at the C-terminus, constructed the plasmid 1; A DNA sequence encoding the Cynomolgus CD8B (XP_005575417.1) (Met1-Pro170) is fused with a polyhistidine tag at the C-terminus, constructed the plasmid 2. The two plasmids are co-expressed and the heterodimer is purified. |
| Molecular Name | CD8A & CD8B Heterodimer |
| Species | Cynomolgus |
| Host | HEK293 Cells |
| Size | 50ug, 100ug, 200ug |
| Protein Family | CD molecule |
| Purity | >95% as determined by SDS-PAGE |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | PBS, pH7.4 |
| Background | CD8A (CD8 Subunit Alpha) is a Protein Coding gene. Diseases associated with CD8A include Cd8 Deficiency, Familial and Herpes Zoster. Among its related pathways are TCR Signaling (Qiagen) and Network map of SARS-CoV-2 signaling pathway. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and coreceptor activity.CD8B (CD8 Subunit Beta) is a Protein Coding gene. Diseases associated with CD8B include Diffuse Large B-Cell Lymphoma and Uterine Corpus Cancer. Among its related pathways are Infectious disease and Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters. Gene Ontology (GO) annotations related to this gene include coreceptor activity and MHC class I protein binding. An important paralog of this gene is CD8B2. |
| Application | WB, ELISA |
| Recommended Dilution | ELISA: 1:100-1:1000 |
| Cross-reactivity | No cross-reactivity with other antigens or proteins. |
| Predicted Molecular Weight | 44.27 kDa |
| Predicted N Terminus | Met 42 |
| Reconstitution | Not applicable. The product is supplied as a ready-to-use liquid formulation. |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Remarks | 收到产品后请立即按保存条件储存；使用前短暂离心，使内容物集中于管底；避免反复冻融。 |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
| Stability | Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
| Molecular Weight | 44.27 kDa |
| Cross-reactivity | No cross-reactivity with other antigens or proteins. |
| Note | 仅供科研使用 |
| ELISA IC50(ppb) | ≥ 1:1000 |
| Function | CD8A (CD8 Subunit Alpha) is a Protein Coding gene. Diseases associated with CD8A include Cd8 Deficiency, Familial and Herpes Zoster. Among its related pathways are TCR Signaling (Qiagen) and Network map of SARS-CoV-2 signaling pathway. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and coreceptor activity.CD8B (CD8 Subunit Beta) is a Protein Coding gene. Diseases associated with CD8B include Diffuse Large B-Cell Lymphoma and Uterine Corpus Cancer. Among its related pathways are Infectious disease and Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters. Gene Ontology (GO) annotations related to this gene include coreceptor activity and MHC class I protein binding. An important paralog of this gene is CD8B2. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
| Temperature Range | -20℃ ~ -80℃ |
| Solubility | 产品为即用型液体，无需复溶。 |
| Appearance | Liquid |
| Product Full Name | Cynomolgus CD8A & CD8B Heterodimer Protein, Flag Tag |
| Preservative Solution | PBS, pH7.4 |
| Usage Method | 冻干粉请按“复溶”说明用无菌去离子水复溶后使用，液体产品可直接使用；具体工作浓度请参考“推荐稀释比例”。 |
| Target | CD8A & CD8B Heterodimer |
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