Human CD275 Protein, His Tag

产品编号

KMP2394

别名

诱导性T细胞促刺激配体, B7 homolog 2, B7-H2

目录价格

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规格

50ug
100ug
200ug

DATASHEET COA

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产品介绍

Alias	诱导性T细胞促刺激配体, B7 homolog 2, B7-H2
Catalog Number	KMP2394
Product Description	The Human CD275 Protein(KMP2394) is produced in HEK293 Cells and the target gene encoding Asp19-Ser258 is expressed with a 6His tag at the C-terminus.
Molecular Name	CD275
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Protein Family	CD molecule
Purity	>95% as determined by SDS-PAGE
Concentration	联系销售经理获得最新批次的浓度
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	20mM PB, 150mM NaCl, 1mM EDTA, pH7.2
Background	Inducible Co-Stimulator Ligand(ICOSLG) belongs to the immunoglobulin superfamily. ICOSLG contains Ig-like C2-type(immunoglobulin-like) domain and 1 Ig-like V-type(immunoglobulin-like) domain. ICOSLG acts as a costimulatory signal for T-cell proliferation and cytokine secretion, it also induces B-cell proliferation and differentiation into plasma cells. It could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function. ICOSLG is widely expressed lymph nodes, leukocytes and spleen, detected on activated monocytes and dendritic cells.
Application	WB, ELISA
Recommended Dilution	ELISA: 1:100-1:1000
Cross-reactivity	No cross-reactivity with other antigens or proteins.
Molecular Formula	KMP2394 SDS-PAGE image1.png
SDS-PAGE
Predicted Molecular Weight	27.51 kDa
Reconstitution	Not applicable. The product is supplied as a ready-to-use liquid formulation.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Remarks	收到产品后请立即按保存条件储存；使用前短暂离心，使内容物集中于管底；避免反复冻融。
Shipping Condition	In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.
Stability	Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Cross-reactivity	No cross-reactivity with other antigens or proteins.
Uniprot ID	O75144
Note	仅供科研使用
ELISA IC50(ppb)	≥ 1:1000
Function	Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (By similarity).
Product Declaration	该产品仅供科研使用，不可直接用于人体或注射。
Temperature Range	-20℃ ~ -80℃
Solubility	产品为即用型液体，无需复溶。
Appearance	Liquid
Product Full Name	Human CD275 Protein
Preservative Solution	20mM PB, 150mM NaCl, 1mM EDTA, pH7.2
Usage Method	冻干粉请按“复溶”说明用无菌去离子水复溶后使用，液体产品可直接使用；具体工作浓度请参考“推荐稀释比例”。
Target	CD275