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Recombinant Human CD360/IL21R Protein, His Tag
Recombinant Human CD360/IL21R Protein, His Tag

Recombinant Human CD360/IL21R Protein, His Tag

产品编号

KMH492

别名

NILR, CD360, IMD56, interleukin 21 receptor

目录价格

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规格
  • 50ug
  • 100ug
产品介绍
AliasNILR, CD360, IMD56, interleukin 21 receptor
Catalog NumberKMH492
Molecular NameIL21R
SpeciesHuman
HostMammalian cells
Size50ug, 100ug
Protein FamilyCD molecule
Purity≥90% as determined by SDS-PAGE
Concentration联系销售经理获得最新批次的浓度
PurificationAffinity Purification
Endotoxin< 1.0 EU per ug of the protein as determined by the LAL method.
FormulationPBS
BackgroundInterleukin 21 Receptor belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2 (IL2) and interleukin 5 (IL5). This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants encoding the same protein have been described.
ApplicationWB, ELISA
Recommended DilutionELISA: 1:100-1:1000
Cross-reactivityNo cross-reactivity with other antigens or proteins.
Predicted Molecular Weight25.96 kDa
Predicted N TerminusMet
ReconstitutionNot applicable. The product is supplied as a ready-to-use liquid formulation.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Remarks收到产品后请立即按保存条件储存;使用前短暂离心,使内容物集中于管底;避免反复冻融。
Shipping ConditionThis product is shipped on ice packs or dry ice.
StabilitySamples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Molecular Weight25.96 kDa
Cross-reactivityNo cross-reactivity with other antigens or proteins.
Uniprot IDQ9HBE5
Note仅供科研使用
ELISA IC50(ppb)≥ 1:1000
FunctionInterleukin 21 Receptor belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2 (IL2) and interleukin 5 (IL5). This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants encoding the same protein have been described.
Product Declaration该产品仅供科研使用,不可直接用于人体或注射。
Temperature Range-20℃ ~ -80℃
Solubility产品为即用型液体,无需复溶。
AppearanceLiquid
Product Full NameRecombinant Human CD360/IL21R Protein
Preservative SolutionPBS
Usage Method冻干粉请按“复溶”说明用无菌去离子水复溶后使用,液体产品可直接使用;具体工作浓度请参考“推荐稀释比例”。
TargetIL21R

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