| Alias | CD158F, KIR2DL5, KIR2DL5.1, KIR2DL5.3, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 5A |
| Catalog Number | KMH338 |
| Molecular Name | KIR2DL5A |
| Species | Human |
| Host | Mammalian cells |
| Size | 50ug, 100ug |
| Protein Family | CD molecule |
| Purity | ≥90% as determined by SDS-PAGE |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purification | Affinity Purification |
| Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
| Formulation | PBS |
| Background | KIR2DL5Ais a 6 kDa type I transmembrane glycoprotein that belongs to the killer cellIg-like receptor (KIR) family. KIRs are expressed on CD56 dim NK cells and Tcell subsets where they regulate effector functions in the innate immunesystem. KIRs are named for the number of Ig-like domains (2D or 3D) in theextracellular domain (ECD), and whether they have long or short (L, S)cytoplasmic tails. Like other inhibiting KIRs, KIR2DL5A has two ITIM domainswithin its long tail however, one of these is atypical and may cause KIR2DL5to be less inhibitory than most inhibiting KIRs. |
| Application | WB, ELISA |
| Recommended Dilution | ELISA: 1:100-1:1000 |
| Cross-reactivity | No cross-reactivity with other antigens or proteins. |
| Predicted Molecular Weight | 26.29 kDa |
| Reconstitution | Not applicable. The product is supplied as a ready-to-use liquid formulation. |
| Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
| Remarks | 收到产品后请立即按保存条件储存;使用前短暂离心,使内容物集中于管底;避免反复冻融。 |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Stability | Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
| Molecular Weight | 26.29 kDa |
| Cross-reactivity | No cross-reactivity with other antigens or proteins. |
| Uniprot ID | Q8N109 |
| Note | 仅供科研使用 |
| ELISA IC50(ppb) | ≥ 1:1000 |
| Function | KIR2DL5Ais a 6 kDa type I transmembrane glycoprotein that belongs to the killer cellIg-like receptor (KIR) family. KIRs are expressed on CD56 dim NK cells and Tcell subsets where they regulate effector functions in the innate immunesystem. KIRs are named for the number of Ig-like domains (2D or 3D) in theextracellular domain (ECD), and whether they have long or short (L, S)cytoplasmic tails. Like other inhibiting KIRs, KIR2DL5A has two ITIM domainswithin its long tail however, one of these is atypical and may cause KIR2DL5to be less inhibitory than most inhibiting KIRs. |
| Product Declaration | 该产品仅供科研使用,不可直接用于人体或注射。 |
| Temperature Range | -20℃ ~ -80℃ |
| Solubility | 产品为即用型液体,无需复溶。 |
| Appearance | Liquid |
| Product Full Name | Recombinant Human CD158F/KIR2DL5A Protein |
| Preservative Solution | PBS |
| Usage Method | 冻干粉请按“复溶”说明用无菌去离子水复溶后使用,液体产品可直接使用;具体工作浓度请参考“推荐稀释比例”。 |
| Target | KIR2DL5A |