Recombinant Human CD146/MCAM Protein, His Tag

产品编号

KMH321

别名

CD146, MUC18, HEMCAM, METCAM, MelCAM, melanoma cell adhesion molecule

目录价格

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规格

50ug
100ug

DATASHEET COA

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产品介绍

Alias	CD146, MUC18, HEMCAM, METCAM, MelCAM, melanoma cell adhesion molecule
Catalog Number	KMH321
Molecular Name	MCAM
Species	Human
Host	Mammalian cells
Size	50ug, 100ug
Protein Family	CD molecule
Purity	≥90% as determined by SDS-PAGE
Concentration	联系销售经理获得最新批次的浓度
Purification	Affinity Purification
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Formulation	PBS
Background	CD146 belongs to the immunoglobulin supergene family with five immunoglobulin like domains (V-V-C2-C2-C2), a transmembrane region and a 63 residue cytoplasmic tail. The protein is a membrane glycoprotein that functions as a Ca2+ independent cell adhesion molecule involved in heterophilic cell to cell interactions. CD146 has a molecular size of 13 kDa in its reduced form (118 kDa unreduced), and N linked glycosylation accounts for fifty percent of the apparent molecular weight. In some cells the molecule carries a sulfate 3 glucuronyl moiety.
Application	WB, ELISA
Recommended Dilution	ELISA: 1:100-1:1000
Cross-reactivity	No cross-reactivity with other antigens or proteins.
Predicted Molecular Weight	61.49 kDa
Predicted N Terminus	Met
Reconstitution	Not applicable. The product is supplied as a ready-to-use liquid formulation.
Storage Condition	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Remarks	收到产品后请立即按保存条件储存；使用前短暂离心，使内容物集中于管底；避免反复冻融。
Shipping Condition	This product is shipped on ice packs or dry ice.
Stability	Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Molecular Weight	61.49 kDa
Cross-reactivity	No cross-reactivity with other antigens or proteins.
Uniprot ID	P43121
Note	仅供科研使用
ELISA IC50(ppb)	≥ 1:1000
Function	CD146 belongs to the immunoglobulin supergene family with five immunoglobulin like domains (V-V-C2-C2-C2), a transmembrane region and a 63 residue cytoplasmic tail. The protein is a membrane glycoprotein that functions as a Ca2+ independent cell adhesion molecule involved in heterophilic cell to cell interactions. CD146 has a molecular size of 13 kDa in its reduced form (118 kDa unreduced), and N linked glycosylation accounts for fifty percent of the apparent molecular weight. In some cells the molecule carries a sulfate 3 glucuronyl moiety.
Product Declaration	该产品仅供科研使用，不可直接用于人体或注射。
Temperature Range	-20℃ ~ -80℃
Solubility	产品为即用型液体，无需复溶。
Appearance	Liquid
Product Full Name	Recombinant Human CD146/MCAM Protein
Preservative Solution	PBS
Usage Method	冻干粉请按“复溶”说明用无菌去离子水复溶后使用，液体产品可直接使用；具体工作浓度请参考“推荐稀释比例”。
Target	MCAM