Recombinant Human CD105/ENG Protein, His Tag
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产品编号
KMH279
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别名
END, HHT1, ORW1, endoglin
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目录价格
联系客服获取报价RMB
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规格
- 50ug
- 100ug
产品介绍
| Alias | END, HHT1, ORW1, endoglin |
| Catalog Number | KMH279 |
| Molecular Name | ENG |
| Species | Human |
| Host | Mammalian cells |
| Size | 50ug, 100ug |
| Protein Family | CD molecule |
| Purity | ≥90% as determined by SDS-PAGE |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purification | Affinity Purification |
| Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
| Formulation | PBS |
| Background | Endoglin is a type I membrane glycoprotein located on cell surfaces and is part of the TGF beta receptor complex. The protein consists of a homodimer of 18 kDa with disulfide links. It has been found on endothelial cells, activated macrophages, fibroblasts, and smooth muscle cells. Endoglin has been found to be part of the TGF-beta1 receptor complex. It thus may be involved in the binding of TGF-beta1, TGF-beta3, activin-A, BMP-2, and BMP-7. Beside TGF-beta signaling endoglin may have other functions. It has been postulated that engoglin is involved in the cytoskeletal organization affecting cell morphology and migration. Endoglin has a role in the development of the cardiovascular system and in vascular remodeling. Its expression is regulated during heart development. Experimental mice without the endoglin gene die due to cardiovascular abnormalities. |
| Application | WB, ELISA |
| Recommended Dilution | ELISA: 1:100-1:1000 |
| Cross-reactivity | No cross-reactivity with other antigens or proteins. |
| Predicted Molecular Weight | 64.46 kDa |
| Predicted N Terminus | Glu 26 |
| Reconstitution | Not applicable. The product is supplied as a ready-to-use liquid formulation. |
| Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
| Remarks | 收到产品后请立即按保存条件储存；使用前短暂离心，使内容物集中于管底；避免反复冻融。 |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Stability | Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
| Molecular Weight | 64.46 kDa |
| Cross-reactivity | No cross-reactivity with other antigens or proteins. |
| Uniprot ID | P17813 |
| Note | 仅供科研使用 |
| ELISA IC50(ppb) | ≥ 1:1000 |
| Function | Endoglin is a type I membrane glycoprotein located on cell surfaces and is part of the TGF beta receptor complex. The protein consists of a homodimer of 18 kDa with disulfide links. It has been found on endothelial cells, activated macrophages, fibroblasts, and smooth muscle cells. Endoglin has been found to be part of the TGF-beta1 receptor complex. It thus may be involved in the binding of TGF-beta1, TGF-beta3, activin-A, BMP-2, and BMP-7. Beside TGF-beta signaling endoglin may have other functions. It has been postulated that engoglin is involved in the cytoskeletal organization affecting cell morphology and migration. Endoglin has a role in the development of the cardiovascular system and in vascular remodeling. Its expression is regulated during heart development. Experimental mice without the endoglin gene die due to cardiovascular abnormalities. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
| Temperature Range | -20℃ ~ -80℃ |
| Solubility | 产品为即用型液体，无需复溶。 |
| Appearance | Liquid |
| Product Full Name | Recombinant Human CD105/ENG Protein |
| Preservative Solution | PBS |
| Usage Method | 冻干粉请按“复溶”说明用无菌去离子水复溶后使用，液体产品可直接使用；具体工作浓度请参考“推荐稀释比例”。 |
| Target | ENG |
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