Rabbit Anti-BHE40/BHLHE40 Polyclonal Antibody
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产品编号
PAV568
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别名
basic helix-loop-helix family member e40, DEC1, HLHB2, BHLHB2, Clast5, SHARP2, STRA13, Stra14, SHARP-2
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规格
- 100ul
产品介绍
| Alias | basic helix-loop-helix family member e40, DEC1, HLHB2, BHLHB2, Clast5, SHARP2, STRA13, Stra14, SHARP-2 |
| Catalog Number | PAV568 |
| Molecular Name | BHLHE40 |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Immunogen | This antibody was raised against from human BHE40 protein |
| Recommended Dilution | WB 1:500-2000 |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
FAQ
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Q1-BHLHE40的生物学相关性是什么？
BHLHE40（DEC1）是转录抑制因子，调控T细胞耗竭及肿瘤免疫逃逸，其高表达与黑色素瘤PD-1耐药相关。
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Q2-是否适用于免疫检查点抑制剂研究？
可以，推荐使用PD-1抗体处理的肿瘤浸润T细胞，通过流式检测BHLHE40与TIM-3的共表达。
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Q3-是否与BHLHE41交叉反应？
经测试无交叉反应，特异性针对BHLHE40。
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