Rabbit Anti-Human ACAN pAb
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产品编号
PA5756
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别名
ACAN, AGC1, AGCAN, CSPG1, CSPGCP, MSK16, SEDK, aggrecan
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规格
- 50ul
- 100ul
Alias | ACAN, AGC1, AGCAN, CSPG1, CSPGCP, MSK16, SEDK, aggrecan |
Catalog Number | PA5756 |
Molecular Name | ACAN |
Host | Rabbit |
Size | 50ul, 100ul |
Clonity | Polyclonal |
Purification | Affinity Purification |
Formulation | Supply in PBS with 0.02% sodium azide, 50% glycerol, pH 7.4. |
Immunogen | A synthetic peptide corresponding to a sequence within a.a. 350-450 of human ACAN (NP_037359.3). |
Application | WB |
Storage Condition | Store the product under sterile conditions after opening at -20℃. Avoid freeze-thaw cycles. |
Shipping Condition | Shipped on ice packs. |
Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
Product Full Name | Rabbit Anti-Human ACAN Polyclonal Antibody |
ACAN(Aggrecan)是软骨基质的主要蛋白多糖,维持关节软骨的弹性和抗压能力,其降解与骨关节炎密切相关。
是的,推荐人关节软骨石蜡切片,需透明质酸酶预处理(37℃, 30分钟)以暴露抗原,抗体稀释1:200。
提供ACAN酶解(如ADAMTS5处理)后WB条带消失的阴性对照数据,预期完整条带约250 kDa(核心蛋白)。
与人ACAN同源性约75%,可部分检测,需预实验优化(推荐起始稀释1:500)。
是的,提供骨关节炎患者软骨组织ACAN表达降低的IHC结果。