Rabbit Anti-Human SMAD3 pAb
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产品编号
PA5430
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别名
HSPC193, HsT17436, JV15-2, LDS1C, LDS3, MADH3, SMAD3
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规格
- 50ul
- 100ul
| Catalog Number | PA5430 |
| Alias | HSPC193, HsT17436, JV15-2, LDS1C, LDS3, MADH3, SMAD3 |
| Size | 50ul, 100ul |
| Product Full Name | Rabbit Anti-Human SMAD3 Polyclonal Antibody |
| Molecular Name | SMAD3 |
| Host | Rabbit |
| Clonity | Polyclonal |
| Purification | Affinity Purification |
| Storage Condition | Store the product under sterile conditions after opening at -20℃. Avoid freeze-thaw cycles. |
| Formulation | Supply in PBS with 0.02% sodium azide, 50% glycerol, pH 7.4. |
| Shipping Condition | Shipped on ice packs. |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to a.a. 1-230 of human Smad3 (NP_005893.1). |
| Application | WB |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
SMAD3是TGF-β信号核心转录因子,介导纤维化、免疫抑制及肿瘤转移,其突变导致Loeys-Dietz综合征(主动脉瘤)及卵巢癌耐药。
可以,推荐使用TGF-β处理的T细胞,检测Foxp3表达上调(Treg细胞分化)。
经测试无交叉反应,特异性针对SMAD3。
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