Rabbit Anti-Human C5AR2 pAb
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产品编号
PA5178
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别名
C5AR2, C5L2, GPF77, GPR77
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规格
- 50ul
- 100ul
| Catalog Number | PA5178 |
| Alias | C5AR2, C5L2, GPF77, GPR77 |
| Size | 50ul, 100ul |
| Product Full Name | Rabbit Anti-Human C5AR2 Polyclonal Antibody |
| Molecular Name | C5AR2 |
| Host | Rabbit |
| Clonity | Polyclonal |
| Purification | Affinity Purification |
| Storage Condition | Store the product under sterile conditions after opening at -20℃. Avoid freeze-thaw cycles. |
| Formulation | Supply in PBS with 0.02% sodium azide, 50% glycerol, pH 7.4. |
| Shipping Condition | Shipped on ice packs. |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to a.a. 258-337 of human C5AR2 (NP_060955.1). |
| Application | WB |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
C5AR2(C5a受体2)是补体C5a的非典型受体,通过β-arrestin信号调控炎症与免疫平衡,其激活与脓毒症、代谢综合征及肿瘤免疫逃逸相关,可能拮抗C5AR1的促炎作用。
可以,推荐使用肥胖或糖尿病小鼠模型,通过流式细胞术检测脂肪组织中C5AR2⁺巨噬细胞的极化状态(如M1/M2比例)。
经测试无交叉反应,特异性针对C5AR2。
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