Rabbit Anti-Human APAF1 pAb
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产品编号
PA4512
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别名
APAF1, APAF-1, CED4
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规格
- 50ul
- 100ul
| Catalog Number | PA4512 |
| Alias | APAF1, APAF-1, CED4 |
| Size | 50ul, 100ul |
| Product Full Name | Rabbit Anti-Human APAF1 Polyclonal Antibody |
| Molecular Name | APAF1 |
| Host | Rabbit |
| Clonity | Polyclonal |
| Purification | Affinity Purification |
| Storage Condition | Store the product under sterile conditions after opening at -20℃. Avoid freeze-thaw cycles. |
| Formulation | Supply in PBS with 0.02% sodium azide, 50% glycerol, pH 7.4. |
| Shipping Condition | Shipped on ice packs. |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to a.a. 1-250 of human APAF1 (NP_863651.1). |
| Application | WB |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
APAF1(凋亡蛋白酶激活因子1)是线粒体凋亡通路的核心组分,与细胞色素c结合后激活Caspase-9,启动Caspase级联反应,调控程序性细胞死亡。
可以,推荐使用依托泊苷或顺铂处理的细胞模型,通过WB检测APAF1与Caspase-9的活化复合体形成。
经测试无交叉反应,特异性针对APAF1。
添加Caspase抑制剂(如Z-VAD-FMK)并快速裂解样本,低温保存。
分装后-20℃保存,稀释后4℃保存不超过1周,有效期2年。
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