Rabbit Anti-Human SMAD4 Polyclonal Antibody
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产品编号
PA11508
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别名
DPC4, JIP, MADH4, MYHRS, Smad4, SMAD4
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规格
- 50ul
- 100ul
Alias | DPC4, JIP, MADH4, MYHRS, Smad4, SMAD4 |
Catalog Number | PA11508 |
Molecular Name | SMAD4 |
Host | Rabbit |
Size | 50ul, 100ul |
Clonity | Polyclonal |
Purification | Affinity Purification |
Formulation | Supply in PBS with 0.02% sodium azide, 50% glycerol, pH 7.4. |
Immunogen | Recombinant fusion protein containing a sequence corresponding to a.a. 160-450 of human Smad4 (NP_005350.1). |
Application | WB, IF |
Storage Condition | Store the product under sterile conditions after opening at -20℃. Avoid freeze-thaw cycles. |
Shipping Condition | Shipped on ice packs. |
Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
SMAD4是TGF-β/BMP信号通路的共同介质(Co-SMAD),介导信号转导与核内转录调控,其突变导致胰腺癌、结直肠癌及遗传性出血性毛细血管扩张症(HHT)。
可以,推荐使用胰腺癌细胞模型,检测SMAD4缺失后的EMT标志物(如Vimentin)上调。
经测试无交叉反应,特异性针对SMAD4。