Rabbit Anti-Human ARHGEF5 pAb
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产品编号
PA10649
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别名
ARHGEF5, GEF5, P60, TIM, TIM1
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规格
- 50ul
- 100ul
Alias | ARHGEF5, GEF5, P60, TIM, TIM1 |
Catalog Number | PA10649 |
Molecular Name | ARHGEF5 |
Host | Rabbit |
Size | 50ul, 100ul |
Clonity | Polyclonal |
Purification | Affinity Purification |
Formulation | Supply in PBS with 0.02% sodium azide, 50% glycerol, pH 7.4. |
Immunogen | Recombinant fusion protein containing a sequence corresponding to a.a. 1248-1597 of human ARHGEF5 (NP_005426.2). |
Application | IHC, IF |
Storage Condition | Store the product under sterile conditions after opening at -20℃. Avoid freeze-thaw cycles. |
Shipping Condition | Shipped on ice packs. |
Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
Product Full Name | Rabbit Anti-Human ARHGEF5 Polyclonal Antibody |
ARHGEF5(Rho鸟苷酸交换因子5)激活Rho GTP酶(如RhoA、Rac1),调控细胞骨架重组、细胞迁移及肿瘤侵袭,其异常表达与乳腺癌和肺癌转移相关。
可以,推荐使用高转移性癌细胞(如MDA-MB-231),通过Transwell实验结合WB检测ARHGEF5表达与迁移能力的相关性。
经测试无交叉反应,特异性针对ARHGEF5。
添加蛋白酶抑制剂混合物,快速裂解样本并低温保存。
分装后-20℃保存,稀释后4℃保存不超过1周,有效期2年。