Rabbit Anti-BMP2 antibody_天津卡梅德科技发展有限公司

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Rabbit Anti-BMP2 antibody

Rabbit Anti-BMP2 antibody

产品编号

MA1576

别名

BMP 2,BMP 2A,BMP-2

规格

50ul
100ul
200ul

DATASHEET MSDS

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产品介绍

Alias	BMP 2,BMP 2A,BMP-2
Catalog Number	MA1576
Product Description	BMP2 belongs to the transforming growth factor-beta (TGFB) superfamily of secreted growth factors. It is a disulfide-linked homodimer and induces bone and cartilage formation. In addition to its osteogenic activity, BMP2 plays an important role in cardiac morphogenesis and is expressed in a variety of tissues including lung, spleen, brain, liver, prostate ovary and small intestine. The functional form of BMP2 is a 26 kDa protein composed of two identical 114 amino acid polypeptide chains linked by a single disulfide bond. BMPs control fundamental events in early embryonic development, organogenesis and adult tissue homeostasis.
Molecular Name	BMP2
Host	Rabbit
Size	50ul,100ul,200ul
Clonity	Polyclonal
Concentration	1mg/ml
Purification	affinity purification
Formulation	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background	BMP2 belongs to the transforming growth factor-beta (TGFB) superfamily of secreted growth factors. It is a disulfide-linked homodimer and induces bone and cartilage formation. In addition to its osteogenic activity, BMP2 plays an important role in cardiac morphogenesis and is expressed in a variety of tissues including lung, spleen, brain, liver, prostate ovary and small intestine. The functional form of BMP2 is a 26 kDa protein composed of two identical 114 amino acid polypeptide chains linked by a single disulfide bond. BMPs control fundamental events in early embryonic development, organogenesis and adult tissue homeostasis.
Immunogen	KLH conjugated synthetic peptide derived from human BMP2: 341-396/396
Application	WB, ELISA, IHC-P, IHC-F, IF
Cross-reactivity	Human, Mouse, Rat, (predicted: Chicken, Dog, Pig, Cow, Horse, Guinea Pig, )
Product Declaration	本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。

FAQ

Q1-BMP2的生物学功能是什么？

BMP2（骨形态发生蛋白2）诱导成骨分化及软骨形成，其重组蛋白用于骨再生治疗，异常表达与骨肉瘤及肺动脉高压相关。
Q2-是否适用于骨组织工程研究？

可以，推荐使用BMP2加载的支架材料，通过Micro-CT和ALP染色评估成骨效果。
Q3-是否与BMP4或BMP7交叉反应？

经测试无交叉反应，特异性针对BMP2。

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