Rabbit Anti-Human AGER pAb
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产品编号
PA6887
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别名
AGER, RAGE, SCARJ1
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规格
- 50ul
- 100ul
| Catalog Number | PA6887 |
| Alias | AGER, RAGE, SCARJ1 |
| Size | 50ul, 100ul |
| Product Full Name | Rabbit Anti-Human AGER Polyclonal Antibody |
| Molecular Name | AGER |
| Host | Rabbit |
| Clonity | Polyclonal |
| Purification | Affinity Purification |
| Storage Condition | Store the product under sterile conditions after opening at -20℃. Avoid freeze-thaw cycles. |
| Formulation | Supply in PBS with 0.02% sodium azide, 50% glycerol, pH 7.4. |
| Shipping Condition | Shipped on ice packs. |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to a.a. 41-340 of human AGER (NP_001127.1). |
| Application | WB |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
AGER(晚期糖基化终产物受体)参与慢性炎症、糖尿病并发症及阿尔茨海默病等,调控NF-κB信号通路。
适用于检测AGER表达水平,但相互作用研究需结合配体结合实验(如ELISA或SPR)。
建议使用RIPA裂解液(含蛋白酶抑制剂)提取膜蛋白,避免过度超声破坏受体完整性。
主要识别人源AGER,与小鼠同源性约85%,需预实验验证交叉反应性。
使用3% H₂O₂阻断内源性过氧化物酶,并优化一抗稀释比例(建议1:200起始)。
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